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Doriana Fruci
Bambino Gesù Children Hospital, Italy
2 protocols
Loredana Cifaldi
Bambino Gesù Children Hospital, Italy
2 protocols
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Franco Locatelli
Bambino Gesù Children Hospital, Italy
Research focus
Immunology
Contributions
2
Author merit
Reviewer merit
Editor merit
2 Protocols published
Peptide Loading on MHC Class I Molecules of Tumor Cells
Authors:
Loredana Cifaldi
,
Franco Locatelli
and
Doriana Fruci
,
date:
09/20/2016,
view:
7017,
Q&A:
0
MHC class I molecules present peptides to cytotoxic T cells allowing the immune system to scan for intracellular pathogens and mutated proteins. The generation of antigenic peptides is a multistep process that ends in the endoplasmic reticulum (ER). ...
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Killer Cell Ig-like Receptors (KIR)-Binding Assay for Tumor Cells
Authors:
Loredana Cifaldi
,
Franco Locatelli
and
Doriana Fruci
,
date:
09/20/2016,
view:
4455,
Q&A:
0
Natural killer (NK) cells play key roles in innate and adaptive immune responses against virus and tumor cells. Their function relies on the dynamic balance between activating and inhibiting signals through receptors that bind ligands expressed on ...
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