Claire Rougeulle University Paris Diderot, Sorbonne Paris Cité, Epigenetics and Cell Fate, France
1 protocol

Céline Vallot
  • University Paris Diderot, Sorbonne Paris Cité, Epigenetics and Cell Fate, France
Research focus
  • Stem cell
  • 1 Author merit


PhD, Université Paris XI - Institut Curie, UMR144 Molecular Oncology Team, Paris, 2009

Current position

CNRS Research Associate (CR2), PhD


  1. Vallot, C., Ouimette, J. F., Makhlouf, M., Feraud, O., Pontis, J., Come, J., Martinat, C., Bennaceur-Griscelli, A., Lalande, M. and Rougeulle, C. (2015). Erosion of X Chromosome Inactivation in Human Pluripotent Cells Initiates with XACT Coating and Depends on a Specific Heterochromatin Landscape. Cell Stem Cell 16(5): 533-546.

  2. Lazorthes, S., Vallot, C., Briois, S., Aguirrebengoa, M., Thuret, J. Y., St Laurent, G., Rougeulle, C., Kapranov, P., Mann, C., Trouche, D. and Nicolas, E. (2015). A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus. Nat Commun 6: 5971.

  3. Vallot, C., Herault, A., Boyle, S., Bickmore, W. A. and Radvanyi, F. (2015). PRC2-independent chromatin compaction and transcriptional repression in cancer. Oncogene 34(6): 741-751.

  4. Vallot, C., Huret, C., Lesecque, Y., Resch, A., Oudrhiri, N., Bennaceur-Griscelli, A., Duret, L. and Rougeulle, C. (2013). XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells. Nat Genet 45(3): 239-241.

  5. Vallot, C., Stransky, N., Bernard-Pierrot, I., Herault, A., Zucman-Rossi, J., Chapeaublanc, E., Vordos, D., Laplanche, A., Benhamou, S., Lebret, T., Southgate, J., Allory, Y. and Radvanyi, F. (2011). A novel epigenetic phenotype associated with the most aggressive pathway of bladder tumor progression. J Natl Cancer Inst 103(1): 47-60.

  6. Estecio, M. R., Gallegos, J., Vallot, C., Castoro, R. J., Chung, W., Maegawa, S., Oki, Y., Kondo, Y., Jelinek, J., Shen, L., Hartung, H., Aplan, P. D., Czerniak, B. A., Liang, S. and Issa, J. P. (2010). Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res 20(10): 1369-1382.

  7. Stransky, N., Vallot, C., Reyal, F., Bernard-Pierrot, I., de Medina, S. G., Segraves, R., de Rycke, Y., Elvin, P., Cassidy, A., Spraggon, C., Graham, A., Southgate, J., Asselain, B., Allory, Y., Abbou, C. C., Albertson, D. G., Thiery, J. P., Chopin, D. K., Pinkel, D. and Radvanyi, F. (2006). Regional copy number-independent deregulation of transcription in cancer. Nat Genet 38(12): 1386-1396.

1 Protocol published
Single-cell Visualization of Chromosome Transcriptional Territories by RNA-paint
Authors:  Céline Vallot and Claire Rougeulle, date: 09/05/2016, view: 7213, Q&A: 0
We developed a FISH-based method to directly assess chromosome-wide transcriptional activity, thereby enabling the visualization of the actively transcribed fraction of a chromosome at the single-cell level. We applied this method to probe the ...
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