Jan Münch Institute of Molecular Virology, Ulm University Medical Center, Germany
1 protocol

Janis A Müller
  • Post-Doc, Philipps University of Marburg
Research focus
  • Microbiology
  • HIV Zika virus sexual transmission
  • 1 Author merit


Msc. in Molecular Medicine, Ulm University, 2011

Current position

PhD student, Institute of Molecular Virology, Ulm University


  1. Lavender, K. J., Gibbert, K., Peterson, K. E., Van Dis, E., Francois, S., Woods, T., Messer, R. J., Gawanbacht, A., Muller, J. A., Munch, J., Phillips, K., Race, B., Harper, M. S., Guo, K., Lee, E. J., Trilling, M., Hengel, H., Piehler, J., Verheyen, J., Wilson, C. C., Santiago, M. L., Hasenkrug, K. J. and Dittmer, U. (2016). Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo. J Virol 90(13): 6001-6013.
  2. Muller, J. A., Zirafi, O., Roan, N. R., Lee, S. J. and Munch, J. (2016). Evaluation of EPI-X4 as a urinary peptide biomarker for diagnosis and prognosis of late acute GvHD. Bone Marrow Transplant.
  3. Zirafi, O., Kim, K. A., Roan, N. R., Kluge, S. F., Muller, J. A., Jiang, S., Mayer, B., Greene, W. C., Kirchhoff, F. and Munch, J. (2014). Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Sci Transl Med 6(262): 262ra157.
  4. Roan, N. R., Liu, H., Usmani, S. M., Neidleman, J., Muller, J. A., Avila-Herrera, A., Gawanbacht, A., Zirafi, O., Chu, S., Dong, M., Kumar, S. T., Smith, J. F., Pollard, K. S., Fandrich, M., Kirchhoff, F., Munch, J., Witkowska, H. E. and Greene, W. C. (2014). Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. J Virol 88(13): 7221-7234.
  5. Usmani, S. M., Zirafi, O., Muller, J. A., Sandi-Monroy, N. L., Yadav, J. K., Meier, C., Weil, T., Roan, N. R., Greene, W. C., Walther, P., Nilsson, K. P., Hammarstrom, P., Wetzel, R., Pilcher, C. D., Gagsteiger, F., Fandrich, M., Kirchhoff, F. and Munch, J. (2014). Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun 5: 3508.
  6. Yolamanova, M., Meier, C., Shaytan, A. K., Vas, V., Bertoncini, C. W., Arnold, F., Zirafi, O., Usmani, S. M., Muller, J. A., Sauter, D., Goffinet, C., Palesch, D., Walther, P., Roan, N. R., Geiger, H., Lunov, O., Simmet, T., Bohne, J., Schrezenmeier, H., Schwarz, K., Standker, L., Forssmann, W. G., Salvatella, X., Khalatur, P. G., Khokhlov, A. R., Knowles, T. P., Weil, T., Kirchhoff, F. and Munch, J. (2013). Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses. Nat Nanotechnol 8(2): 130-136.
  7. Roan, N. R., Muller, J. A., Liu, H., Chu, S., Arnold, F., Sturzel, C. M., Walther, P., Dong, M., Witkowska, H. E., Kirchhoff, F., Munch, J. and Greene, W. C. (2011). Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell Host Microbe 10(6): 541-550.
1 Protocol published
Reporter Assay for Semen-mediated Enhancement of HIV-1 Infection
Authors:  Janis A. Müller and Jan Münch, date: 07/20/2016, view: 9365, Q&A: 0
Semen contains amyloid fibrils that enhance HIV-1 infection (Münch et al., 2007; Kim et al., 2010; Roan et al., 2011; Arnold et al., 2012; Usmani et al., 2014; Roan et al., 2014). Positively ...
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