Alexandros Alexandratos National and Kapodistrian University of Athens
62 protocols

Emilie Battivelli Buck institute
5 protocols

Fei Xiao Stanford University
1 protocol

Guangzhi Zhang Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China
4 protocols

Editor
Emilie Besnard
  • Research scientist, BioAge Labs
Research focus
  • Cell biology
  • mTOR signaling
    HIV latency and transcription
    Cell biology, senescence and aging
  • 0 Author merit
5 Protocols reviewed
Induction of Acute or Disseminating Bacterial Pneumonia in Mice and Sampling of Infected Organs for Studying the Host Response to Bacterial Pneumonia
Authors:  Wanhai Qin, Zhe Liu, Tom van der Poll and Alex F. de Vos, date: 01/05/2022, view: 872, Q&A: 0

Experimental pneumonia models are important tools to study the pathophysiology of lung inflammation caused by microbial infections and the efficacy of (novel) drugs. We have applied a murine model of pneumonia induced by Pseudomonas (P.) aeruginosa

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High-throughput Flow Cytometry Assay to Investigate TDP43 Splicing Function
Authors:  H. Broder Schmidt and Rajat Rohatgi, date: 04/20/2020, view: 3070, Q&A: 0
Mutations in RNA-binding proteins (RBPs) such as TDP43 are associated with transcriptome-wide splicing defects and cause severe neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The impact ...
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6 Protocols edited
TZA, a Sensitive Reporter Cell-based Assay to Accurately and Rapidly Quantify Inducible, Replication-competent Latent HIV-1 from Resting CD4+ T Cells
Authors:  Anwesha Sanyal, Vatsala S. Rangachar and Phalguni Gupta, date: 05/20/2019, view: 5406, Q&A: 1
The latent HIV-1 viral reservoir in resting CD4+ (rCD4+) T cells represents a major barrier to an HIV-1 cure. There is an ongoing effort to identify therapeutic approaches that will eliminate or reduce the size of this ...
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Lentiviral Knockdown of Transcription Factor STAT1 in Peromyscus leucopus to Assess Its Role in the Restriction of Tick-borne Flaviviruses
Authors:  Adaeze O. Izuogu and R. Travis Taylor, date: 12/05/2017, view: 8108, Q&A: 0
Cellular infection with tick-borne flaviviruses (TBFVs) results in activation of the interferon (IFN) signaling pathway and subsequent upregulation of numerous genes termed IFN stimulated genes (ISGs) (Schoggins et al., 2011). Many ISGs ...
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