Richard Wyatt Department of Immunology and Microbial Science, The Scripps Research Institute, USA
2 protocols

Jidnyasa Ingale
  • The Scripps Research Institute
Research focus
  • Immunology
  • 2 Author merit


PhD in Biochemistry and Bio-Organic Chemistry, The University Of Georgia, Athens, GA, USA, 2009

Current position

Research Associate (Prof. Richard Wyatt), The Scripps Research Institute, La Jolla, CA, USA (2013- present)


  1. Phad, G. E., Bernat, N. V., Feng, Y., Ingale, J., Murillo, P. A. M., O’Dell, S., Li, Y., Mascola, J. R., Sundling, C. and Wyatt, R. T. (2015). Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization. The Journal of Immunology: 1500122.
  2. Feng, Y., Jiang, H., Ingale, J., McKee, K., Mascola, J. and Wyatt, R. (2014). Antigenicity and Immunogenicity of Disulfide-stabilized HIV-1 Envelope Glycoprotein Oligomers. AIDS research and human retroviruses 30(S1): A84-A85.
  3. Ingale, J., Tran, K., Kong, L., Dey, B., McKee, K., Schief, W., Kwong, P. D., Mascola, J. R. and Wyatt, R. T. (2014). Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies. J Virol 88(24): 14002-14016.
  4. Gaekwad, J., Reeves, J., Wolfert, M. A. and Boons, G. J. (2010). Modulation of TLR4 activation with different synthetic lipid A derivatives. Journal of Biological Chemistry 285 (38): 29375-86.
  5. Zhang, Y., Gaekwad, J., Wolfert, M. A. and Boons, G.-J. (2008). Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4. Organic & biomolecular chemistry 6(18): 3371-3381.
  6. Zhang, Y., Gaekwad, J., Wolfert, M. A. and Boons, G. J. (2008). Innate immune responses of synthetic lipid A derivatives of Neisseria meningitidis. Chemistry-A European Journal 14(2): 558-569.
  7. Ingale, S., Wolfert, M. A., Gaekwad, J., Buskas, T. and Boons, G.-J. (2007). Robust immune responses elicited by a fully synthetic three-component vaccine. Nature chemical biology 3(10): 663-667.
  8. Zhang, Y., Gaekwad, J., Wolfert, M. A. and Boons, G.-J. (2007). Modulation of innate immune responses with synthetic lipid A derivatives. Journal of the American Chemical Society 129(16): 5200-5216.
2 Protocols published
Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores
Authors:  Jidnyasa Ingale and Richard T Wyatt, date: 10/05/2015, view: 6208, Q&A: 0
Kinetic analysis of antibodies is one of the important studies for characterization of antibodies and screening of ligands. In our recent study (Ingale et al., 2014), we compared the antigenic profiles and binding characteristics of four ...
Coupling of HIV-1 gp120-derived Core Protein to Paramagnetic Beads and Adsorption Assays
Authors:  Jidnyasa Ingale and Richard T Wyatt, date: 10/05/2015, view: 5327, Q&A: 0
Analysis of the functional activity in polyclonal serum following immunization of a complex protein or glycoprotein immunogen is a very important but tedious process. Fine mapping of epitope-specific antibodies is difficult when they are elicited at ...
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