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Coauthors
Noriko Toyama-Sorimachi Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Japan
1 protocol

Tsubasa Tanaka Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Japan
1 protocol

Toshihiko Kobayashi
  • Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Japan
  • 1 Author merit

Education

Ph.D., Department of Pathology, Immunology, and Microbiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan, 2007

Current position

Chief, Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan

Publications (representative)

  1. Kobayashi, T., Shimabukuro-Demoto, S., Yoshida-Sugitani, R., Furuyama-Tanaka, K., Karyu, H., Sugiura, Y., Shimizu, Y., Hosaka, T., Goto, M., Kato, N., Okamura, T., Suematsu, M., Yokoyama, S. and Toyama-Sorimachi, N. (2014). The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production. Immunity 41(3): 375-388.
  2. Kobayashi, T., Tanaka, T. and Toyama-Sorimachi, N. (2013). How do cells optimize luminal environments of endosomes/lysosomes for efficient inflammatory responses? J Biochem 154(6): 491-499.
  3. Anthony, R. M., Kobayashi, T., Wermeling, F. and Ravetch, J. V. (2011). Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway. Nature 475(7354): 110-113.
  4. Blumenthal, A., Kobayashi, T., Pierini, L. M., Banaei, N., Ernst, J. D., Miyake, K. and Ehrt, S. (2009). RP105 facilitates macrophage activation by Mycobacterium tuberculosis lipoproteins. Cell Host Microbe 5(1): 35-46.
  5. Kobayashi, T., Takahashi, K., Nagai, Y., Shibata, T., Otani, M., Izui, S., Akira, S., Gotoh, Y., Kiyono, H. and Miyake, K. (2008). Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice. Int Immunol 20(7): 881-891.

1 Protocol published
Separation of Intracellular Vesicles for Immunoassays
Authors:  Toshihiko Kobayashi, Tsubasa Tanaka and Noriko Toyama-Sorimachi, date: 08/20/2015, view: 3576, Q&A: 0
The endosome/lysosome systems play important roles in immune cell functions as signaling platforms. Immune cells utilize these endosome/lysosome for signal transduction or intercellular communication to elicit the proper immune responses, regulating ...