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Coauthors
Wei Cui Institute of Reproductive and Developmental Biology, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, UK
1 protocol
Coreviewers
Hui Zhu Stanford University
17 protocols

Miao He Fudan University
2 protocols

Nicoletta Cordani University of Milano-Bicocca
20 protocols

Oneil Bhalala Baker Institute
44 protocols

Reviewer
Patrick Ovando-Roche
  • Post-Doc, Harvard Medical School.
Research focus
  • Stem cell
  • Stem Cells. Retina. Brain. Neurology. Spinocerebellar Ataxia. Parkinson's Disease
  • 1 Author merit

Education

PhD, Imperial College London, 2014

Lab information

Vikram Khurana Lab.
http://khuranalab.bwh.harvard.edu/team/

Publications

1. Ovando-Roche, P., J. S. Yu, S. Testori, C. Ho and W. Cui (2014). "TRF2-Mediated Stabilization of hREST4 Is Critical for the Differentiation and Maintenance of Neural Progenitors." Stem Cells 32(8): 2111-2122. DOI: 10.1002/stem.1725

2. Ovando-Roche, P and W. Cui (2015). "Identification of Factors in Regulating a Protein Ubiquitination by Immunoprecipitation: a Case Study of TRF2 on Human REST4 Ubiquitination". Bio-protocol 5(13): e1525. DOI: 10.21769/BioProtoc.1525

3. Ovando-Roche, P., G. Annastasios, A. J. Smith, R. A. Pearson and Ali, R.R (2017). "Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration." Current Stem Cell Reports 3: 112. DOI:10.1007/s40778-017-0078-4.
1 Protocol published
Identification of Factors in Regulating a Protein Ubiquitination by Immunoprecipitation: a Case Study of TRF2 on Human REST4 Ubiquitination
Authors:  Wei Cui and Patrick Ovando-Roche, date: 07/05/2015, view: 5184, Q&A: 0
Ubiquitination is the first step of the ubiquitin-proteasome pathway that regulates cells for their homeostatic functions and is an enzymatic, protein post-translational modification process in which ubiquitin is transferred to a target protein ...
4 Protocols reviewed
Induction of Photothrombotic Stroke in the Sensorimotor Cortex of Rats and Preparation of Tissue for Analysis of Stroke Volume and Topographical Cortical Localization of Ischemic Infarct
Authors:  Anna M. Wiersma and Ian R. Winship, date: 05/20/2018, view: 1136, Q&A: 0
The photothrombotic model of stroke is commonly used in research as it allows the ischemic infarct to be targeted to specific regions of the cortex with high reproducibility and well-defined infarct borders. Unlike other models of stroke, ...
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Quantitative Live-cell Reporter Assay for Noncanonical Wnt Activity
Authors:  Edith P. Karuna, Michael W. Susman and Hsin-Yi Henry Ho, date: 03/20/2018, view: 1513, Q&A: 0
Noncanonical Wnt signaling functions independently of the β-catenin pathway to control diverse developmental processes, and dysfunction of the pathway contributes to a number of human pathological conditions, including birth defects and metastatic ...
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