Wei Cui Institute of Reproductive and Developmental Biology, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, UK
1 protocol
Anthony Flamier Stem Cell and Developmental Biology Laboratory
4 protocols

Hui Zhu Stanford University
18 protocols

Miao He Institutes of Brain Science Fudan University
13 protocols

Nicoletta Cordani University of Milano-Bicocca
25 protocols

Patrick Ovando-Roche
  • Biotech engineer, CRISPR Therapeutics
Research focus
  • Stem cell
  • Stem Cells. Retina. Brain. Neurology. Spinocerebellar Ataxia. Parkinson's Disease
  • 1 Author merit


PhD, Imperial College London, 2014


1. Ovando-Roche, P., E. L. West, M. J. Branch, R. D. Sampson, M. Fernando, P. Munro, A. Georgiadis, M. Rizzi, M. Kloc, A. Naeem, J. Ribeiro, A. J. Smith, A. Gonzalez-Cordero and R. R. Ali (2018). "Use of bioreactors for culturing human retinal organoids improves photoreceptor yields." Stem Cell Res Ther 9(1): 156.

2. Gonzalez Cordero, A., D. Goh, K. Kruczek, A. Naeem, M. Fernando, S. M. Kleine Holthaus, M. Takaaki, S. J. I. Blackford, M. Kloc, L. Agundez, R. D. Sampson, S. Borooah, P. Ovando-Roche, M. S. Mehat, E. L. West, A. J. Smith, R. A. Pearson and R. R. Ali (2018). "Assessment of AAV vector tropisms for mouse and human pluripotent stem cell-derived RPE and photoreceptor cells." Hum Gene Ther.

3. Ovando-Roche, P., A. Georgiadis, A. J. Smith, R. A. Pearson and R. R. Ali (2017). "Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration." Curr Stem Cell Rep 3(2): 112-123.

4. Ovando-Roche, P., J. S. Yu, S. Testori, C. Ho and W. Cui (2014). "TRF2-mediated stabilization of hREST4 is critical for the differentiation and maintenance of neural progenitors." Stem Cells 32(8): 2111-2122.
1 Protocol published
Identification of Factors in Regulating a Protein Ubiquitination by Immunoprecipitation: a Case Study of TRF2 on Human REST4 Ubiquitination
Authors:  Wei Cui and Patrick Ovando-Roche, date: 07/05/2015, view: 9962, Q&A: 0
Ubiquitination is the first step of the ubiquitin-proteasome pathway that regulates cells for their homeostatic functions and is an enzymatic, protein post-translational modification process in which ubiquitin is transferred to a target protein ...
6 Protocols reviewed
Integration of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons into Rat Brain
Authors:  Xiling Yin, Ted M. Dawson and Valina L. Dawson, date: 09/05/2020, view: 2844, Q&A: 0
Human neuron transplantation offers novel opportunities for modeling human neurologic diseases and potentially replacement therapies. However, the complex structure of the human cerebral cortex, which is organized in six layers with tightly ...
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Papain-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry
Authors:  Hanadie Yousef, Cathrin J Czupalla, Davis Lee, Eugene C Butcher and Tony Wyss-Coray, date: 11/20/2018, view: 6807, Q&A: 0
Brain endothelial cells (BECs) form the integral component of the blood-brain barrier (BBB) which separates the systemic milieu from the brain parenchyma and protects the brain from pathogens and circulating factors. In order to study BEC biology, ...
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