Education
Ph.D., Institute of Biophysics, CAS, Beijing, China
Current position
Postdoc, New England Biolabs Inc. (since 2015)
Publications
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Ren, G., Champion, M. M. and Huntley, J. F. (2014). Identification of disulfide bond isomerase substrates reveals bacterial virulence factors. Mol Microbiol 94(4): 926-944.
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Quan, S., Koldewey, P., Tapley, T., Kirsch, N., Ruane, K. M., Pfizenmaier, J., Shi, R., Hofmann, S., Foit, L., Ren, G., Jakob, U., Xu, Z., Cygler, M. and Bardwell, J. C. (2011). Genetic selection designed to stabilize proteins uncovers a chaperone called Spy. Nat Struct Mol Biol 18(3): 262-269.
Note: This paper was the subject of a News and Views in Nature: Powers, E. T. and Balch, W. E. (2011). Protein folding: Protection from the outside. Nature 471(7336): 42-43.
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Ren, G. and Bardwell, J. C. (2011). Engineered pathways for correct disulfide bond oxidation. Antioxid Redox Signal 14(12): 2399-2412.
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Foit, L.*, Mueller-Schickert, A.*, Mamathambika, B. S., Gleiter, S., Klaska, C. L., Ren, G. and Bardwell, J. C. (2011). Genetic selection for enhanced folding in vivo targets the Cys14-Cys38 disulfide bond in bovine pancreatic trypsin inhibitor. Antioxid Redox Signal 14(6): 973-984.
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Li, H.*, Ke, H.*, Ren, G., Qiu, X., Weng, Y. X. and Wang, C. C. (2009). Thermal-induced dissociation and unfolding of homodimeric DsbC revealed by temperature-jump time-resolved infrared spectra. Biophys J 97(10): 2811-2819.
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Ren, G., Stephan, D., Xu, Z., Zheng, Y., Tang, D., Harrison, R. S., Kurz, M., Jarrott, R., Shouldice, S. R., Hiniker, A., Martin, J. L., Heras, B. and Bardwell, J. C. (2009). Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue. J Biol Chem 284(15): 10150-10159.
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Hiniker, A., Ren, G., Heras, B., Zheng, Y., Laurinec, S., Jobson, R. W., Stuckey, J. A., Martin, J. L. and Bardwell, J. C. (2007). Laboratory evolution of one disulfide isomerase to resemble another. Proc Natl Acad Sci U S A 104(28): 11670-11675.
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Ren, G.*, Wang, X.*, Hao, S., Hu, H. and Wang, C. C. (2007). Translocation of alpha-synuclein expressed in Escherichia coli. J Bacteriol 189(7): 2777-2786.
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Huang, C., Ren, G., Zhou, H. and Wang, C. C. (2005). A new method for purification of recombinant human alpha-synuclein in Escherichia coli. Protein Expr Purif 42(1): 173-177.
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Ren, G., Lin, Z., Tsou, C. L. and Wang, C. C. (2003). Effects of macromolecular crowding on the unfolding and the refolding of D-glyceraldehyde-3-phosophospate dehydrogenase. J Protein Chem 22(5): 431-439.
*Contributed equally