Douglas Richman University of California San Diego, USA
1 protocol

Steven Lada University of California San Diego, La Jolla
1 protocol

Sara Gianella University of California San Diego, USA
2 protocols

Marta Massanella University of California San Diego, USA
2 protocols

Matthew C. Strain
  • University of California San Diego, USA
Research focus
  • Microbiology
  • 1 Author merit


M. D., University of California San Diego, 2005
Ph.D. in Physics, University of California San Diego, 2002

Current position

Assistant Professor, Division of Infectious Diseases, UCSD (2014-present)
Associate Director, Genomics & Sequencing Core, UCSD Center for AIDS Research (2014-present)


  1. Strain, M. C., Lada, S. M., Luong, T., Rought, S. E., Gianella, S., Terry, V. H., Spina, C. A., Woelk, C. H. and Richman, D. D. (2013). Highly precise measurement of HIV DNA by droplet digital PCR. PLoS One 8(4): e55943.
  2. Strain, M. C. and Richman, D. D. (2013). New assays for monitoring residual HIV burden in effectively treated individuals. Curr Opin HIV AIDS 8(2): 106-110.
  3. Yukl, S. A., Boritz, E., Busch, M., Bentsen, C., Chun, T. W., Douek, D., Eisele, E., Haase, A., Ho, Y. C., Hutter, G., Justement, J. S., Keating, S., Lee, T. H., Li, P., Murray, D., Palmer, S., Pilcher, C., Pillai, S., Price, R. W., Rothenberger, M., Schacker, T., Siliciano, J., Siliciano, R., Sinclair, E., Strain, M., Wong, J., Richman, D. and Deeks, S. G. (2013). Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog 9(5): e1003347.
  4. Eriksson, S., Graf, E. H., Dahl, V., Strain, M. C., Yukl, S. A., Lysenko, E. S., Bosch, R. J., Lai, J., Chioma, S., Emad, F., Abdel-Mohsen, M., Hoh, R., Hecht, F., Hunt, P., Somsouk, M., Wong, J., Johnston, R., Siliciano, R. F., Richman, D. D., O'Doherty, U., Palmer, S., Deeks, S. G. and Siliciano, J. D. (2013). Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. PLoS Pathog 9(2): e1003174.
  5. Persaud, D., Gay, H., Ziemniak, C., Chen, Y. H., Piatak, M., Jr., Chun, T. W., Strain, M., Richman, D. and Luzuriaga, K. (2013). Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med 369(19): 1828-1835.
  6. Archin, N. M., Liberty, A. L., Kashuba, A. D., Choudhary, S. K., Kuruc, J. D., Crooks, A. M., Parker, D. C., Anderson, E. M., Kearney, M. F., Strain, M. C., Richman, D. D., Hudgens, M. G., Bosch, R. J., Coffin, J. M., Eron, J. J., Hazuda, D. J. and Margolis, D. M. (2012). Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 487(7408): 482-485.
  7. Yukl, S., Pillai, S., Li, P., Chang, K., Pasutti, W., Ahlgren, C., Havlir, D., Strain, M., Gunthard, H., Richman, D., Rice, A. P., Daar, E., Little, S. and Wong, J. K. (2009). Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity. Virology 387(1): 98-108.
  8. Strain, M. C., Little, S. J., Daar, E. S., Havlir, D. V., Gunthard, H. F., Lam, R. Y., Daly, O. A., Nguyen, J., Ignacio, C. C., Spina, C. A., Richman, D. D. and Wong, J. K. (2005). Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J Infect Dis 191(9): 1410-1418.
  9. Havlir, D. V., Koelsch, K. K., Strain, M. C., Margot, N., Lu, B., Ignacio, C. C., Miller, M. D., Wong, J. K. and Gilead 903 Study, T. (2005). Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine. J Infect Dis 191(7): 1164-1168.
  10. Strain, M. C., Gunthard, H. F., Havlir, D. V., Ignacio, C. C., Smith, D. M., Leigh-Brown, A. J., Macaranas, T. R., Lam, R. Y., Daly, O. A., Fischer, M., Opravil, M., Levine, H., Bacheler, L., Spina, C. A., Richman, D. D. and Wong, J. K. (2003). Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proc Natl Acad Sci U S A 100(8): 4819-4824.
1 Protocol published
外周血单核细胞中DNA总量及 2-LTR (长末端重复序列) HIV DNA、HIV RNA 和 疱疹病毒 DNA 的量化
Authors:  Marta Massanella, Sara Gianella, Steven M. Lada, Douglas D. Richman and Matthew C. Strain, date: 06/05/2015, view: 10958, Q&A: 0
Almost all individuals infected with human immunodeficiency virus (HIV) are also infected with cytomegalovirus (CMV) and Epstein Barr virus (EBV). The aims of our studies have included characterizing and measuring the latent HIV reservoir and ...
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