Alexandros Alexandratos National and Kapodistrian University of Athens
48 protocols

Alka Mehra Institute of Genomics and Integrative Biology
40 protocols

Arsalan Daudi University of California
157 protocols

ASWAD KHADILKAR UNIVERSITY OF CALIFORNIA SANTA CRUZ
11 protocols

Editor
Prashanth N Suravajhala
  • Research scientist, Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, India
Research focus
  • Cancer biology
  • Systems Biology, Next Generation Sequencing, Functional Genomics, non-coding RNA
  • 5 Author merit

Education

PhD, Aalborg University

Lab information

Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Statue Circle, Jaipur 302001 RJ, India
http://bisr.res.in/profile_prash.php

Publications

5 Protocols published
Extraction of DNA and RNA from Formalin-fixed Paraffin-embedded Tissue Specimens

One of the most common methods for isolating biomolecules from clinical samples is using TRIzol. While many tissues are freshly frozen, a large number of tissues are formalin-fixed paraffin-embedded (FFPE) blocks for pathology and diagnostics.

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12 Protocols reviewed
EmPC-seq: Accurate RNA-sequencing and Bioinformatics Platform to Map RNA Polymerases and Remove Background Error

Transcription errors can substantially affect metabolic processes in organisms by altering the epigenome and causing misincorporations in mRNA, which is translated into aberrant mutant proteins. Moreover, within eukaryotic genomes there are specific

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Understanding Docking Complexes of Macromolecules Using HADDOCK: The Synergy between Experimental Data and Computations
Authors:  Andrea Saponaro, Vincenzo Maione, Alexandre M. J. J. Bonvin and Francesca Cantini, date: 10/20/2020, view: 1279, Q&A: 0
This protocol illustrates the modelling of a protein-peptide complex using the synergic combination of in silico analysis and experimental results. To this end, we use the integrative modelling software HADDOCK, which possesses the powerful ...
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9 Protocols edited
Detecting Differentially Methylated Promoters in Genes Related to Disease Phenotypes Using R
Authors:  Jordi Martorell Marugán and Pedro Carmona-Sáez, date: 06/05/2021, view: 1028, Q&A: 0

DNA methylation in gene promoters plays a major role in gene expression regulation, and alterations in methylation patterns have been associated with several diseases. In this context, different software suites and statistical methods have been

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Production of Phenotypically Uniform Human Cerebral Organoids from Pluripotent Stem Cells
Authors:  Adam Sivitilli, Parisa Ghiasi and Liliana Attisano, date: 04/20/2021, view: 1981, Q&A: 0

Recent advances in stem cell technology have allowed researchers to generate 3D cerebral organoids (COs) from human pluripotent stem cells (hPSCs). Indeed, COs have provided an unprecedented opportunity to model the developing human brain in a 3D

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