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Coauthors
Rolf Brekken Department of Surgery, Hamon Center for Therapeutic Oncology Research, USA
1 protocol
Coreviewers
Guillermo Gomez University of South Australia
5 protocols

HongLok Lung University of Hong Kong
56 protocols

Vivien Coulson-Thomas University of Houston
15 protocols

Reviewer
Kristina Y. Aguilera
  • Post-Doc, University of California, Los Angeles
Research focus
  • Cancer biology
  • 1 Author merit

Education

Ph.D., University of Texas Southwestern Medical Center

1 Protocol published
Hypoxia Studies with Pimonidazole in vivo
Authors:  Kristina Y. Aguilera and Rolf A. Brekken, date: 10/05/2014, view: 11967, Q&A: 0
Therapy-induced hypoxia drives changes in the tumor microenvironment that contribute to the poor response to therapy. Hypoxia is capable of driving the expression and/or activation of specific signaling cascades (e.g., c-Met, Axl, CTGF), ...
2 Protocols reviewed
Mouse Mammary Intraductal (MIND) Method for Transplantation of Patient Derived Primary DCIS Cells and Cell Lines
Authors:  Frances Kittrell, Kelli Valdez, Hanan Elsarraj, Yan Hong, Daniel Medina and Fariba Behbod, date: 03/05/2016, view: 3501, Q&A: 0
The MIND method involves intraductal injection of patient derived ductal carcinoma in situ (DCIS) cells and DCIS cell lines (MCF10DCIS.COM and SUM225) inside the mouse mammary ducts [Video 1 and Figure 1 in Behbod et al. (2009)]. This ...
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Isolation and Flow-cytometric Analysis of Mouse Intestinal Crypt Cells
Authors:  Dayanira Alsina-Beauchamp, Paloma del Reino and Ana Cuenda, date: 11/05/2015, view: 5486, Q&A: 0
The intestinal epithelial layer forms tubular invaginations into the underlying connective tissue of the lamina propria. These structures, termed crypts, are the basic functional unit of the intestine. Colon crypts and the surrounding lamina propria ...
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