Claudia Kemper MRC Centre for Transplantation, King's College, UK
1 protocol
Alexandros Kokotos Weill Cornell Medicine
13 protocols

Alka Mehra Institute of Genomics and Integrative Biology
36 protocols

Cody Kime Center of Developmental Biology, RIKEN
2 protocols

Elizabeth Clarke Center for Health Research-Kaiser Permanente
6 protocols

Reviewer
Martin V Kolev
  • Investigator Complement Biology, GSK Research and Development
Research focus
  • Immunology
  • T cells, intracellular complement, metabolism
  • 1 Author merit

Education

PhD, Cardiff University

Publications

Keeping It All Going-Complement Meets Metabolism. Kolev M, Kemper C.
Front Immunol. 2017 Jan 18;8:1. doi: 10.3389/fimmu.2017.00001. eCollection 2017. Review.

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses.
Kolev M, Dimeloe S, Le Friec G, Navarini A, Arbore G, Povoleri GA, Fischer M, Belle R, Loeliger J, Develioglu L, Bantug GR, Watson J, Couzi L, Afzali B, Lavender P, Hess C, Kemper C.
Immunity. 2015 Jun 16;42(6):1033-47. doi: 10.1016/j.immuni.2015.05.024.
Complement--tapping into new sites and effector systems.
Kolev M, Le Friec G, Kemper C.
Nat Rev Immunol. 2014 Dec;14(12):811-20. doi: 10.1038/nri3761. Epub 2014 Nov 14. Review.
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.
Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C.
Immunity. 2013 Dec 12;39(6):1143-57. doi: 10.1016/j.immuni.2013.10.018. Epub 2013 Dec 5.
1 Protocol published
Enzymatic Reactions and Detection of C3 Cleavage Fragments
Authors:  Claudia Kemper and Martin Kolev, date: 08/20/2014, view: 8470, Q&A: 0
The complement component C3 is the major effector molecule of the complement system. C3 circulates in the blood and interstitial fluids as pro-enzyme and is activated by enzymatic cleavage into a C3a portion, a classic anaphylatoxin that functions ...
15 Protocols reviewed
Identification of Target Protein for Bio-active Small Molecule Using Photo-cross Linked Beads and MALDI-TOF Mass Spectrometry
Development of methods for protein identification is one of the important aspects of proteomics. Here, we report a protocol for the preparation of compound conjugated beads by photo-crosslinking, affinity purification, gel electrophoresis, and ...
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A Yeast Chromatin-enriched Fractions Purification Approach, yChEFs, from Saccharomyces cerevisiae
We have adapted a previous procedure and improved an approach that we named yChEFs (yeast Chromatin Enriched Fractions) for purifying chromatin fractions. This methodology allows the easy, reproducible and scalable recovery of proteins associated ...
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