Claudia Kemper MRC Centre for Transplantation, King's College, UK
1 protocol
Alexandros Kokotos Weill Cornell Medicine
18 protocols

Alka Mehra Institute of Genomics and Integrative Biology
41 protocols

Cody Kime Center of Developmental Biology, RIKEN
2 protocols

Elizabeth Clarke Center for Health Research-Kaiser Permanente
6 protocols

Advisor
Martin V Kolev
  • Associate Director, Apellis Pharmaceuticals
Research focus
  • Immunology
  • T cells, intracellular complement, metabolism
  • 1 Author merit

Education

PhD, Cardiff University

Publications

1 Protocol published
Enzymatic Reactions and Detection of C3 Cleavage Fragments
Authors:  Claudia Kemper and Martin Kolev, date: 08/20/2014, view: 9710, Q&A: 0
The complement component C3 is the major effector molecule of the complement system. C3 circulates in the blood and interstitial fluids as pro-enzyme and is activated by enzymatic cleavage into a C3a portion, a classic anaphylatoxin that functions ...
17 Protocols reviewed
Intracellular IRF5 Dimerization Assay
Authors:  Cherrie D. Sherman and Betsy J. Barnes, date: 05/20/2021, view: 2556, Q&A: 0

The intracellular interferon regulatory factor 5 (IRF5) dimerization assay is a technique designed to measure molecular interaction(s) with endogenous IRF5. Here, we present two methods that detect endogenous IRF5 homodimerization and interaction of

...
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In vitro Measurement of Membrane Attack Complex in RPE Cells
Authors:  Kelly Mulfaul and Sarah L. Doyle, date: 02/20/2021, view: 2025, Q&A: 0

Initiation of the complement system results in the formation of a multiprotein pore termed the membrane attack complex (MAC, C5b-C9). MAC pores accumulate on a cell surface and can result in cell lysis. The retinal pigment epithelium (RPE) is a

...
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