Martin V Kolev —BIO-PROTOCOL

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Claudia Kemper MRC Centre for Transplantation, King's College, UK
1 protocol

Alexandros Kokotos Weill Cornell Medicine
18 protocols

Alka Mehra Institute of Genomics and Integrative Biology
41 protocols

Cody Kime Center of Developmental Biology, RIKEN
2 protocols

Elizabeth Clarke Center for Health Research-Kaiser Permanente
6 protocols

Advisor

Martin V Kolev

Associate Director, Apellis Pharmaceuticals

Research focus

Immunology
T cells, intracellular complement, metabolism

1 Author merit
Reviewer merit
Editor merit

Education

PhD, Cardiff University

Publications

https://pubmed.ncbi.nlm.nih.gov/?term=Kolev,Martin[Author]

1 Protocol published

Enzymatic Reactions and Detection of C3 Cleavage Fragments

Authors: Claudia Kemper and Martin Kolev, date: 08/20/2014, view: 9606, Q&A: 0

The complement component C3 is the major effector molecule of the complement system. C3 circulates in the blood and interstitial fluids as pro-enzyme and is activated by enzymatic cleavage into a C3a portion, a classic anaphylatoxin that functions ...

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17 Protocols reviewed

Intracellular IRF5 Dimerization Assay

Authors: Cherrie D. Sherman and Betsy J. Barnes, date: 05/20/2021, view: 2382, Q&A: 0

The intracellular interferon regulatory factor 5 (IRF5) dimerization assay is a technique designed to measure molecular interaction(s) with endogenous IRF5. Here, we present two methods that detect endogenous IRF5 homodimerization and interaction of

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In vitro Measurement of Membrane Attack Complex in RPE Cells

Authors: Kelly Mulfaul and Sarah L. Doyle, date: 02/20/2021, view: 1880, Q&A: 0

Initiation of the complement system results in the formation of a multiprotein pore termed the membrane attack complex (MAC, C5b-C9). MAC pores accumulate on a cell surface and can result in cell lysis. The retinal pigment epithelium (RPE) is a

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