Martin V Kolev —BIO-PROTOCOL

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Claudia Kemper MRC Centre for Transplantation, King's College, UK
1 protocol

Alexandros Kokotos Weill Cornell Medicine
16 protocols

Alka Mehra Institute of Genomics and Integrative Biology
39 protocols

Cody Kime Center of Developmental Biology, RIKEN
2 protocols

Elizabeth Clarke Center for Health Research-Kaiser Permanente
6 protocols

Reviewer

Martin V Kolev

Investigator Complement Biology, GSK Research and Development

Research focus

Immunology
T cells, intracellular complement, metabolism

1 Author merit
Reviewer merit
Editor merit

Education

PhD, Cardiff University

Publications

Keeping It All Going-Complement Meets Metabolism. Kolev M, Kemper C.
Front Immunol. 2017 Jan 18;8:1. doi: 10.3389/fimmu.2017.00001. eCollection 2017. Review.

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses.
Kolev M, Dimeloe S, Le Friec G, Navarini A, Arbore G, Povoleri GA, Fischer M, Belle R, Loeliger J, Develioglu L, Bantug GR, Watson J, Couzi L, Afzali B, Lavender P, Hess C, Kemper C.
Immunity. 2015 Jun 16;42(6):1033-47. doi: 10.1016/j.immuni.2015.05.024.
Complement--tapping into new sites and effector systems.
Kolev M, Le Friec G, Kemper C.
Nat Rev Immunol. 2014 Dec;14(12):811-20. doi: 10.1038/nri3761. Epub 2014 Nov 14. Review.
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.
Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C.
Immunity. 2013 Dec 12;39(6):1143-57. doi: 10.1016/j.immuni.2013.10.018. Epub 2013 Dec 5.

1 Protocol published

Enzymatic Reactions and Detection of C3 Cleavage Fragments

Authors: Claudia Kemper and Martin Kolev, date: 08/20/2014, view: 9061, Q&A: 0

The complement component C3 is the major effector molecule of the complement system. C3 circulates in the blood and interstitial fluids as pro-enzyme and is activated by enzymatic cleavage into a C3a portion, a classic anaphylatoxin that functions ...

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16 Protocols reviewed

In vitro Measurement of Membrane Attack Complex in RPE Cells

Authors: Kelly Mulfaul and Sarah L. Doyle, date: 02/20/2021, view: 776, Q&A: 0

Initiation of the complement system results in the formation of a multiprotein pore termed the membrane attack complex (MAC, C5b-C9). MAC pores accumulate on a cell surface and can result in cell lysis. The retinal pigment epithelium (RPE) is a

...

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Identification of Target Protein for Bio-active Small Molecule Using Photo-cross Linked Beads and MALDI-TOF Mass Spectrometry

Authors: Kruthi Suvarna, Kaori Honda, Makoto Muroi, Yasumitsu Kondoh, Nobumoto Watanabe and Hiroyuki Osada, date: 02/05/2020, view: 2339, Q&A: 0

Development of methods for protein identification is one of the important aspects of proteomics. Here, we report a protocol for the preparation of compound conjugated beads by photo-crosslinking, affinity purification, gel electrophoresis, and ...

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