Georg Schett Department of Internal Medicine 3, University of Erlangen-Nuremberg, Institute of Rheumatology and Immunology, Germany
1 protocol

Gerhard Krönke Department of Internal Medicine 3, University of Erlangen-Nuremberg, Institute of Rheumatology and Immunology, Germany
1 protocol

Carina Scholtysek
  • Department of Internal Medicine 3, University of Erlangen-Nuremberg, Institute of Rheumatology and Immunology, Germany
  • 1 Author merit

Education

Ph.D. in Biology, Department for Internal Medicine 3, Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nuremberg

Current position

Postdoc, Department for Internal Medicine 3, Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nuremberg

Publications

  1. Ipseiz, N., Uderhardt, S., Scholtysek, C., Steffen, M., Schabbauer, G., Bozec, A., Schett, G. and Krönke, G. (2014). The nuclear receptor Nr4a1 mediates anti-inflammatory effects of apoptotic cells. J Immunol 192(10): 4852-4858.
  2. Stock, M., Bohm, C., Scholtysek, C., Englbrecht, M., Furnrohr, B. G., Klinger, P., Gelse, K., Gayetskyy, S., Engelke, K., Billmeier, U., Wirtz, S., van den Berg, W. and Schett, G. (2013). Wnt inhibitory factor 1 deficiency uncouples cartilage and bone destruction in tumor necrosis factor alpha-mediated experimental arthritis. Arthritis Rheum 65(9): 2310-2322.
  3. Scholtysek, C., Katzenbeisser, J., Fu, H., Uderhardt, S., Ipseiz, N., Stoll, C., Zaiss, M. M., Stock, M., Donhauser, L., Bohm, C., Kleyer, A., Hess, A., Engelke, K., David, J. P., Djouad, F., Tuckermann, J. P., Desvergne, B., Schett, G. and Krönke, G. (2013). PPARbeta/delta governs Wnt signaling and bone turnover. Nat Med 19(5): 608-613.
  4. Lin, N. Y., Beyer, C., Giessl, A., Kireva, T., Scholtysek, C., Uderhardt, S., Munoz, L. E., Dees, C., Distler, A., Wirtz, S., Krönke, G., Spencer, B., Distler, O., Schett, G. and Distler, J. H. (2013). Autophagy regulates TNFalpha-mediated joint destruction in experimental arthritis. Ann Rheum Dis 72(5): 761-768.
  5. Kleyer, A., Scholtysek, C., Bottesch, E., Hillienhof, U., Beyer, C., Distler, J. H., Tuckermann, J. P., Schett, G. and Krönke, G. (2012). Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss. J Bone Miner Res 27(12): 2442-2451.
  6. Bohm, C., Derer, A., Axmann, R., Hillienhoff, U., Zaiss, M. M., Luther, J., Zech, C., Stock, M., Scholtysek, C., Engelke, K., Hess, A., Tuckermann, J. P., Schett, G. and David, J. P. (2012). RSK2 protects mice against TNF-induced bone loss. J Cell Sci 125(Pt 9): 2160-2171.
  7. Scholtysek, C., Krönke, G. and Schett, G. (2012). Inflammation-associated changes in bone homeostasis. Inflamm Allergy Drug Targets 11(3): 188-195.
  8. Krönke, G., Reich, N., Scholtysek, C., Akhmetshina, A., Uderhardt, S., Zerr, P., Palumbo, K., Lang, V., Dees, C., Distler, O., Schett, G. and Distler, J. H. (2012). The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis. Ann Rheum Dis 71(6): 1081-1087.
  9. Zaiss, M. M., Kurowska-Stolarska, M., Bohm, C., Gary, R., Scholtysek, C., Stolarski, B., Reilly, J., Kerr, S., Millar, N. L., Kamradt, T., McInnes, I. B., Fallon, P. G., David, J. P., Liew, F. Y. and Schett, G. (2011). IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss. J Immunol 186(11): 6097-6105
  10. Kronke, G., Uderhardt, S., Kim, K. A., Stock, M., Scholtysek, C., Zaiss, M. M., Surmann-Schmitt, C., Luther, J., Katzenbeisser, J., David, J. P., Abdollahi-Roodsaz, S., Tran, K., Bright, J. M., Binnerts, M. E., Akhmetshina, A., Bohm, C., Distler, J. H., Joosten, L. A., Schett, G. and Abo, A. (2010). R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway. Arthritis Rheum 62(8): 2303-2312.
  11. Kronke, G., Katzenbeisser, J., Uderhardt, S., Zaiss, M. M., Scholtysek, C., Schabbauer, G., Zarbock, A., Koenders, M. I., Axmann, R., Zwerina, J., Baenckler, H. W., van den Berg, W., Voll, R. E., Kuhn, H., Joosten, L. A. and Schett, G. (2009). 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis. J Immunol 183(5): 3383-3389.
  12. Scholtysek, C., Krukiewicz, A. A., Alonso, J. L., Sharma, K. P., Sharma, P. C. and Goldmann, W. H. (2009). Characterizing components of the Saw Palmetto Berry Extract (SPBE) on prostate cancer cell growth and traction. Biochem Biophys Res Commun 379(3): 795-798.
1 Protocol published
Bone Resorption Assay
Authors:  Carina Scholtysek, Gerhard Krönke and Georg Schett, date: 07/20/2014, view: 8082, Q&A: 0
The Bone resorption assay provides an easy to use protocol for quantitatively measuring in vitro osteoclast-mediated bone resorption. Osteoclasts can be seeded onto the bone slices and formation of resorption pits can be quantified via ...
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