Todd Klaenhammer Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, USA
1 protocol

Yong Jun Jun Goh
  • North Carolina State University
Research focus
  • Microbiology
  • 1 Author merit


Ph.D. in Food Science & Technology (Specialization: Food Microbiology), Department of Food Science & Technology, University of Nebraska-Lincoln

Current Position

Research Scientist, Department of Food, Bioprocessing & Nutrition Sciences, North Carolina State University


  1. Selle, K., Goh, Y. J., O'Flaherty, S. and Klaenhammer, T. (2014). Development of an integration mutagenesis system in Lactobacillus gasseri. Gut Microbes 5(3). (Epub ahead of print)
  2. Møller, M. S., Goh, Y. J., Viborg, A. H., Andersen, J. M., Klaenhammer, T. R., Svensson, B. and Hachem, M. A. (2014). Recent insight in α-glucan metabolism in probiotic bacteria. Biologia 69(6): 713-721.
  3. Hutkins, R. and Goh, Y. J. (2014). Streptococcus: Streptococcus thermophiles. In: Batt, C. A. and Tortorello M. L. (eds). Encyclopedia of Food Microbiology. Elsevier Ltd, 554-559.
  4. Goh, Y. J. and Klaenhammer, T. R. (2013). A functional glycogen biosynthesis pathway in Lactobacillus acidophilus: expression and analysis of the glg operon. Mol Microbiol 89(6): 1187-1200.
  5. Johnson, B., Selle, K., O'Flaherty, S., Goh, Y. J. and Klaenhammer, T. (2013). Identification of extracellular surface-layer associated proteins in Lactobacillus acidophilus NCFM. Microbiology 159(Pt 11): 2269-2282.
  6. Andersen, J. M., Barrangou, R., Abou Hachem, M., Lahtinen, S. J., Goh, Y. J., Svensson, B. and Klaenhammer, T. R. (2013). Transcriptional analysis of oligosaccharide utilization by Bifidobacterium lactis Bl-04. BMC Genomics 14: 312.
  7. Abou Hachem, M., Andersen, J. M., Barrangou, R., Møller, M. S., Fredslund, F., Majumder, A., Ejby, M., Lahtinen, S. J., Jacobsen, S. and Lo Leggio, L. (2013). Recent insight into oligosaccharide uptake and metabolism in probiotic bacteria. Biocatalysis and Biotransformation 31(4): 226-235.
  8. Abou Hachem, M., Møller, M. S., Andersen, J. M., Fredslund, F., Majumder, A., Nakai, H., Leggio, L. l., Goh, Y.-J., Barrangou, R. and Klaenhammer, T. R. (2013). A snapshot into the metabolism of isomalto-oligosaccharides in probiotic bacteria. Journal of Applied Glycoscience 60(2): 95-100.
  9. Blatchford, P., Ansell, J., de Godoy, M. R. C., Fahey, G., Garcia-Mazcorro, J. F., Gibson, G. R., Goh, Y. J., Hotchkiss, A. T., Hutkins, R. Rastall, C. L. Reimer, R. A., R., Schoterman, M., Sinderen, D. V., Venema, K. and Whelan, K. (2013). Prebiotic mechanisms, functions and applications. J. Probiotics Prebiotics. In press.
  10. Andersen, J. M., Barrangou, R., Hachem, M. A., Lahtinen, S. J., Goh, Y. J., Svensson, B. and Klaenhammer, T. R. (2012). Transcriptional analysis of prebiotic uptake and catabolism by Lactobacillus acidophilus NCFM. PLoS One 7(9): e44409.
  11. Rodrigues da Cunha, L., Fortes Ferreira, C. L., Durmaz, E., Goh, Y. J., Sanozky-Dawes, R. and Klaenhammer, T. (2012). Characterization of Lactobacillus gasseri isolates from a breast-fed infant. Gut Microbes 3(1): 15-24.
  12. Zadeh, M., Khan, M. W., Goh, Y. J., Selle, K., Owen, J. L., Klaenhammer, T. and Mohamadzadeh, M. (2012). Induction of intestinal pro-inflammatory immune responses by lipoteichoic acid. J Inflamm (Lond) 9: 7.
  13. Goh, Y. J., Goin, C., O'Flaherty, S., Altermann, E. and Hutkins, R. (2011). Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9. Microb Cell Fact 10 Suppl 1: S22.
  14. Douglas, G. L., Goh, Y. J. and Klaenhammer, T. R. (2011). Integrative food grade expression system for lactic acid bacteria. Methods Mol Biol 765: 373-387.
  15. Andersen, J. M., Barrangou, R., Abou Hachem, M., Lahtinen, S., Goh, Y. J., Svensson, B. and Klaenhammer, T. R. (2011). Transcriptional and functional analysis of galactooligosaccharide uptake by lacS in Lactobacillus acidophilus. Proc Natl Acad Sci U S A 108(43): 17785-17790.
  16. Goh, Y. J. and Klaenhammer, T. R. (2010). Functional roles of aggregation-promoting-like factor in stress tolerance and adherence of Lactobacillus acidophilus NCFM. Appl Environ Microbiol 76(15): 5005-5012.
  17. Goh, Y. J., Azcarate-Peril, M. A., O'Flaherty, S., Durmaz, E., Valence, F., Jardin, J., Lortal, S. and Klaenhammer, T. R. (2009). Development and application of a upp-based counterselective gene replacement system for the study of the S-layer protein SlpX of Lactobacillus acidophilus NCFM. Appl Environ Microbiol 75(10): 3093-3105.
  18. Goh, Y. J. and Klaenhammer, T. R. (2009). Genomic features of Lactobacillus species. Front Biosci (Landmark Ed) 14: 1362-1386.
  19. O’ Flaherty, S., Goh, Y. J. and Klaenhammer, T. R. (2009). Genomics of probiotic bacteria. In: Charalampopoulos, D. and Rastall, R. A. (eds). Prebiotics and Probiotics Science and Technology. Springer, 681-723.
  20. Klaenhammer, T. R., Altermann, E., Pfeiler, E., Buck, B. L., Goh, Y. J., O'Flaherty, S., Barrangou, R. and Duong, T. (2008). Functional genomics of probiotic Lactobacilli. J Clin Gastroenterol 42 Suppl 3 Pt 2: S160-162.
  21. Azcarate-Peril, M. A., Altermann, E., Goh, Y. J., Tallon, R., Sanozky-Dawes, R. B., Pfeiler, E. A., O'Flaherty, S., Buck, B. L., Dobson, A., Duong, T., Miller, M. J., Barrangou, R. and Klaenhammer, T. R. (2008). Analysis of the genome sequence of Lactobacillus gasseri ATCC 33323 reveals the molecular basis of an autochthonous intestinal organism. Appl Environ Microbiol 74(15): 4610-4625.
  22. Goh, Y. J., Lee, J. H. and Hutkins, R. W. (2007). Functional analysis of the fructooligosaccharide utilization operon in Lactobacillus paracasei 1195. Appl Environ Microbiol 73(18): 5716-5724.
  23. Goh, Y. J., Zhang, C., Benson, A. K., Schlegel, V., Lee, J. H. and Hutkins, R. W. (2006). Identification of a putative operon involved in fructooligosaccharide utilization by Lactobacillus paracasei. Appl Environ Microbiol 72(12): 7518-7530.
  24. Makarova, K., Slesarev, A., Wolf, Y., Sorokin, A., Mirkin, B., Koonin, E., Pavlov, A., Pavlova, N., Karamychev, V., Polouchine, N., Shakhova, V., Grigoriev, I., Lou, Y., Rohksar, D., Lucas, S., Huang, K., Goodstein, D. M., Hawkins, T., Plengvidhya, V., Welker, D., Hughes, J., Goh, Y., Benson, A., Baldwin, K., Lee, J. H., Diaz-Muniz, I., Dosti, B., Smeianov, V., Wechter, W., Barabote, R., Lorca, G., Altermann, E., Barrangou, R., Ganesan, B., Xie, Y., Rawsthorne, H., Tamir, D., Parker, C., Breidt, F., Broadbent, J., Hutkins, R., O'Sullivan, D., Steele, J., Unlu, G., Saier, M., Klaenhammer, T., Richardson, P., Kozyavkin, S., Weimer, B. and Mills, D. (2006). Comparative genomics of the lactic acid bacteria. Proc Natl Acad Sci U S A 103(42): 15611-15616.
1 Protocol published
Intracellular Glycogen Assays
Authors:  Yong Jun Goh and Todd R. Klaenhammer, date: 06/05/2014, view: 11248, Q&A: 0
Glycogen, a soluble multi-branched glucose homopolysaccharide, is composed of chains of α-1,4-linked glucose residues interconnected by α-1,6-linked branches. The classical biosynthetic pathway involves phosphoglucomutase (Pgm), glucose-1-phosphate ...
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