Immunostaining Protocol: P-Stat3 (Xenograft and Mice)
Authors: Alexandre Calon,
Elisa Espinet,
Sergio Palomo-Ponce,
Daniele V. F. Tauriello,
Mar Iglesias,
María Virtudes Céspedes,
Marta Sevillano,
Cristina Nadal,
Peter Jung,
Xiang H.-F. Zhang,
Daniel Byrom,
Antoni Riera,
David Rossell,
Ramón Mangues,
Joan Massague,
Elena Sancho and
Eduard Batlle,
date: 05/05/2014,
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We sought to understand the mechanisms behind the potent effect of stromal TGF-beta program on the capacity of colorectal cancer (CRC) cells to initiate metastasis. We discovered that mice subcutaneous tumors and metastases generated in the context ...