Joan Massague —BIO-PROTOCOL

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Eduard Batlle Oncology Programme, Institute for Research in Biomedicine, Spain
2 protocols

Elena Sancho Oncology Programme, Institute for Research in Biomedicine, Spain
2 protocols

Ramón Mangues IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Spain
2 protocols

David Rossell Biostatistics and Bioinformatics Unit, Institute for Research in Biomedicine, Spain
2 protocols

Joan Massague

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, USA

2 Author merit
Reviewer merit
Editor merit

2 Protocols published

Immunostaining Protocol: P-Stat3 (Xenograft and Mice)

Authors: Alexandre Calon, Elisa Espinet, Sergio Palomo-Ponce, Daniele V. F. Tauriello, Mar Iglesias, María Virtudes Céspedes, Marta Sevillano, Cristina Nadal, Peter Jung, Xiang H.-F. Zhang, Daniel Byrom, Antoni Riera, David Rossell, Ramón Mangues, Joan Massague, Elena Sancho and Eduard Batlle, date: 05/05/2014, view: 5305, Q&A: 0

We sought to understand the mechanisms behind the potent effect of stromal TGF-beta program on the capacity of colorectal cancer (CRC) cells to initiate metastasis. We discovered that mice subcutaneous tumors and metastases generated in the context ...

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Immunostaining Protocol: P-Smad2 (Xenograft and Mice)

Metastasis depends on a gene program expressed by the tumor microenvironment upon TGF-beta stimulation. CRC (Colorectal cancer) cell lines did not induce robust stromal TGF-beta responses when injected into nude mice as shown by lack of p-SMAD2 ...

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