Eduard Batlle Oncology Programme, Institute for Research in Biomedicine, Spain
2 protocols

Elena Sancho Oncology Programme, Institute for Research in Biomedicine, Spain
2 protocols

Joan Massague Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, USA
2 protocols

Ramón Mangues IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Spain
2 protocols

Sergio Palomo-Ponce
  • Oncology Programme, Institute for Research in Biomedicine, Spain
  • 2 Author merit
2 Protocols published
Immunostaining Protocol: P-Stat3 (Xenograft and Mice)
We sought to understand the mechanisms behind the potent effect of stromal TGF-beta program on the capacity of colorectal cancer (CRC) cells to initiate metastasis. We discovered that mice subcutaneous tumors and metastases generated in the context ...
Immunostaining Protocol: P-Smad2 (Xenograft and Mice)
Metastasis depends on a gene program expressed by the tumor microenvironment upon TGF-beta stimulation. CRC (Colorectal cancer) cell lines did not induce robust stromal TGF-beta responses when injected into nude mice as shown by lack of p-SMAD2 ...
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