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Joan Massague
Cancer Biology & Genetics, Memorial Sloan Kettering Cancer Center, United States
4 protocols
Eduard Batlle
Colorectal Cancer Laboratory, Institute for Research in Biomedicine, Spain
3 protocols
Xiang Zhang
Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, USA
3 protocols
Elena Sancho
Oncology Programme, Institute for Research in Biomedicine, Spain
2 protocols
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Alexandre Calon
Oncology Programme, Institute for Research in Biomedicine, Spain
Research focus
Cancer biology
Contributions
2
Author merit
Reviewer merit
Editor merit
2 Protocols published
Immunostaining Protocol: P-Stat3 (Xenograft and Mice)
Authors:
Alexandre Calon
,
Elisa Espinet
,
Sergio Palomo-Ponce
,
Daniele V. F. Tauriello
,
Mar Iglesias
,
María Virtudes Céspedes
,
Marta Sevillano
,
Cristina Nadal
,
Peter Jung
,
Xiang H.-F. Zhang
,
Daniel Byrom
,
Antoni Riera
,
David Rossell
,
Ramón Mangues
,
Joan Massague
,
Elena Sancho
and
Eduard Batlle
,
date:
05/05/2014,
view:
8215,
Q&A:
0
We sought to understand the mechanisms behind the potent effect of stromal TGF-beta program on the capacity of colorectal cancer (CRC) cells to initiate metastasis. We discovered that mice subcutaneous tumors and metastases generated in the context ...
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Immunostaining Protocol: P-Smad2 (Xenograft and Mice)
Authors:
Alexandre Calon
,
Elisa Espinet
,
Sergio Palomo-Ponce
,
Daniele V. F. Tauriello
,
Mar Iglesias
,
María Virtudes Céspedes
,
Marta Sevillano
,
Cristina Nadal
,
Peter Jung
,
Xiang H.-F. Zhang
,
Daniel Byrom
,
Antoni Riera
,
David Rossell
,
Ramón Mangues
,
Joan Massague
,
Elena Sancho
and
Eduard Batlle
,
date:
05/05/2014,
view:
6203,
Q&A:
0
Metastasis depends on a gene program expressed by the tumor microenvironment upon TGF-beta stimulation. CRC (Colorectal cancer) cell lines did not induce robust stromal TGF-beta responses when injected into nude mice as shown by lack of p-SMAD2 ...
More >
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