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Coauthors
Norbert Sträter Center for Biotechnology and Biomedicine, University Leipzig, Germany
1 protocol

Michael Schlömann Environmental Microbiology IÖZ, Technical University "Bergakademie" Freiberg, Germany
1 protocol

Stefan Kaschabek Environmental Microbiology IÖZ, Technical University "Bergakademie" Freiberg, Germany
1 protocol

Janosch Gröning Environmental Microbiology IÖZ, Technical University "Bergakademie" Freiberg, Germany
1 protocol
Coreviewers
Damián Lobato-Márquez Imperial College London
3 protocols

Lionel Schiavolin Institut de Biologie de l'École Normale Supérieure
6 protocols

Maria Sinetova Laboratory of Intracellular Regulation, Institute of Plant Physiology, Russian Academy of Sciences, Russia
44 protocols

Valentine Trotter Lawrence Berkeley National Laboratory
54 protocols

Reviewer
Christian Roth
  • University of York
Research focus
  • Biophysics
  • 1 Author merit

Education

Ph.D. in Structural Biology, University of Leipzig, Germany, 2013

Current position

PostDoc, University of York, UK (since 06/2013)

Publications

  1. Darby, J. F., Landström, J., Roth, C., He, Y., Davies, G. J. and Hubbard, R. E. (2014). Discovery of Selective Small‐Molecule Activators of a Bacterial Glycoside Hydrolase. Angew Chem Int Ed Engl. (Epub ahead of print)
  2. He, Y., Roth, C., Turkenburg, J. P. and Davies, G. J. (2014). Three-dimensional structure of a Streptomyces sviceus GNAT acetyltransferase with similarity to the C-terminal domain of the human GH84 O-GlcNAcase. Acta Crystallogr D Biol Crystallogr 70(Pt 1): 186-195.
  3. Roth, C., Wei, R., Oeser, T., Then, J., Follner, C., Zimmermann, W. and Strater, N. (2014). Structural and functional studies on a thermostable polyethylene terephthalate degrading hydrolase from Thermobifida fusca. Appl Microbiol Biotechnol 98(18): 7815-7823.
  4. Roth, C., Groning, J. A., Kaschabek, S. R., Schlomann, M. and Strater, N. (2013). Crystal structure and catalytic mechanism of chloromuconolactone dehalogenase ClcF from Rhodococcus opacus 1CP. Mol Microbiol 88(2): 254-267.
  5. Roth, C., Kaschabek, S. R., Groning, J. A., Handrek, T., Schlomann, M. and Strater, N. (2012). Crystallization and preliminary characterization of chloromuconolactone dehalogenase from Rhodococcus opacus 1CP. Acta Crystallogr Sect F Struct Biol Cryst Commun 68(Pt 5): 591-595.
  6. Lincke, J., Lassig, D., Kobalz, M., Bergmann, J., Handke, M., Mollmer, J., Lange, M., Roth, C., Moller, A., Staudt, R. and Krautscheid, H. (2012). An isomorphous series of cubic, copper-based triazolyl isophthalate MOFs: linker substitution and adsorption properties. Inorg Chem 51(14): 7579-7586.
  7. Groning, J. A., Roth, C., Kaschabek, S. R., Strater, N. and Schlomann, M. (2012). Recombinant expression of a unique chloromuconolactone dehalogenase ClcF from Rhodococcus opacus 1CP and identification of catalytically relevant residues by mutational analysis. Arch Biochem Biophys 526(1): 69-77.
  8. Dahms, S. O., Kuester, M., Streb, C., Roth, C., Strater, N. and Than, M. E. (2013). Localization and orientation of heavy-atom cluster compounds in protein crystals using molecular replacement. Acta Crystallogr D Biol Crystallogr 69(Pt 2): 284-297.
  9. MüMuller, M. Q., Roth, C., Strater, N. and Sinz, A. (2008). Expression and purification of the ligand-binding domain of peroxisome proliferator-activated receptor alpha (PPARalpha). Protein Expr Purif 62(2): 185-189.
1 Protocol published
Purification and Crystallization of Chloromuconolactone Dehalogenase ClcF from Rhodococcus opacus 1CP
The protocol describes the generation of variants of chloromuconolactone dehalogenase from Rhodococcus opacus (R. opacus) 1CP. ClcF is a multimeric protein, which catalyses the dechlorination of 5-chloromuconolactone to cis ...
5 Protocols reviewed
Estimation of the Chromosomal Copy Number in Synechococcus elongatus PCC 7942
Authors:  Satoru Watanabe and Hirofumi Yoshikawa, date: 07/05/2016, view: 3544, Q&A: 0
Cyanobacteria are prokaryotic organisms that perform oxygenic photosynthesis. Freshwater cyanobacteria, such as Synechococcus elongatus PCC 7942 and Synechocystis sp. PCC 6803, are model organisms for the study of ...
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Determination of Mannitol-2-dehydrogenase Activity
Authors:  Agnès Groisillier and Thierry Tonon, date: 11/05/2015, view: 3729, Q&A: 0
Mannitol is a polyol that occurs in a wide range of living organisms, where it fulfills different physiological roles. Several pathways have been described for the metabolism of mannitol by bacteria, including the phosphoenolpyruvate-dependent ...
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