Elisa Penna Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Italy
1 protocol

Daniela Taverna
  • Deptartment of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Italy
Research focus
  • Cancer biology
  • 1 Author merit


Ph.D. in Cellular and Molecular Biology, Friedrich Miescher Institute, University of Basel, Switzerland, 1993

Current position

Associate Professor in Molecular Biology and Principal Investigator, Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Italy


10 relevant publications

  1. Penna, E., Orso, F., Cimino, D., Vercellino, I., Grassi, E., Quaglino, E., Turco, E. and Taverna, D. (2013). miR-214 coordinates melanoma progression by upregulating ALCAM through TFAP2 and miR-148b downmodulation. Cancer Res 73(13): 4098-4111.
  2. Pincini, A., Tornillo, G., Orso, F., Sciortino, M., Bisaro, B., Leal Mdel, P., Lembo, A., Brizzi, M. F., Turco, E., De Pitta, C., Provero, P., Medico, E., Defilippi, P., Taverna, D.* and Cabodi, S.* (2013). Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells. Cell Cycle 12(15): 2409-2422. *equal contribution.
  3. Elsarraj, H. S., Hong, Y., Valdez, K., Carletti, M., Salah, S. M., Raimo, M., Taverna, D., Prochasson, P., Bharadwaj, U., Tweardy, D. J., Christenson, L. K. and Behbod, F. (2013). A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance. J Cell Sci 126(Pt 11): 2446-2458.
  4. Cimino, D., De Pitta, C., Orso, F., Zampini, M., Casara, S., Penna, E., Quaglino, E., Forni, M., Damasco, C., Pinatel, E., Ponzone, R., Romualdi, C., Brisken, C., De Bortoli, M., Biglia, N., Provero, P., Lanfranchi, G. and Taverna, D. (2013). miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1. FASEB J 27(3): 1223-1235.
  5. Penna, E., Orso, F., Cimino, D., Tenaglia, E., Lembo, A., Quaglino, E., Poliseno, L., Haimovic, A., Osella-Abate, S., De Pitta, C., Pinatel, E., Stadler, M. B., Provero, P., Bernengo, M. G., Osman, I. and Taverna, D. (2011). microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C. EMBO J 30(10): 1990-2007.
  6. Dentelli, P., Rosso, A., Orso, F., Olgasi, C., Taverna, D. and Brizzi, M. F. (2010). microRNA-222 controls neovascularization by regulating signal transducer and activator of transcription 5A expression. Arterioscler Thromb Vasc Biol 30(8): 1562-1568.
  7. Orso, F., Cora, D., Ubezio, B., Provero, P., Caselle, M. and Taverna, D. (2010). Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes. BMC Genomics 11: 355.
  8. Cabodi, S. and Taverna, D. (2010). Interfering with inflammation: a new strategy to block breast cancer self-renewal and progression? Breast Cancer Res 12(2): 305.
  9. Orso, F., Jager, R., Calogero, R. A., Schorle, H., Sismondi, P., De Bortoli, M. and Taverna, D. (2009). AP-2alpha regulates migration of GN-11 neurons via a specific genetic programme involving the Axl receptor tyrosine kinase. BMC Biol 7: 25.
  10. Taverna, D., Moher, H., Crowley, D., Borsig, L., Varki, A. and Hynes, R. O. (2004). Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins. Proc Natl Acad Sci U S A 101(3): 763-768.
1 Protocol published
Authors:  Elisa Penna and Daniela Taverna, date: 02/20/2014, view: 12344, Q&A: 1
Tumor metastases develop when disseminated intravascular cancer cells acquire the ability to arrest by adhering to the capillary walls of distant organs, actively extravasate into their parenchyma, proliferate and establish secondary colonies. The ...
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