Seong-Wook Lee Molecular Biology Department, Dankook University, Republic of Korea
1 protocol
David Paul Medical Research Council
12 protocols

Yannick Debing Janssen Pharmaceutica
27 protocols

Yu Chen Wuhan University
4 protocols

Reviewer
Chang Ho Ho Lee
  • Dankook University
Research focus
  • Molecular biology
  • 1 Author merit

Education

Ph.D., Department of Molecular Biology, Dankook University, Yongin, Korea, 2012

Current position

Research Assistant professor, Department of Molecular Biology, Dankook University (03/2013-present)

Publications

Research articles

  1. Chang, B., Lee, C. H., Lee, J. H. and Lee, S. W. (2010). Comparative analysis of intracellular inhibition of hepatitis C virus replication by small interfering RNAs. Biotechnol Lett 32(9): 1231-1237.
  2. Kwon, B. S., Jeong, J. S., Won, Y. S., Lee, C. H., Yoon, K. S., Hyung Jung, M., Kim, I. H. and Lee, S. W. (2011). Intracellular efficacy of tumor-targeting group I intron-based trans-splicing ribozyme. J Gene Med 13(2): 89-100.
  3. Lee, C. H., Kim, J. H., Kim, H. W., Myung, H. and Lee, S. W. (2012). Hepatitis C virus replication-specific inhibition of microRNA activity with self-cleavable allosteric ribozyme. Nucleic Acid Ther 22(1): 17-29.
  4. Lee, C. H., Lee, Y. J., Kim, J. H., Lim, J. H., Kim, J. H., Han, W., Lee, S. H., Noh, G. J. and Lee, S. W. (2013). Inhibition of hepatitis C virus (HCV) replication by specific RNA aptamers against HCV NS5B RNA replicase. J Virol 87(12): 7064-7074.
    (Selected as ‘Press Release’ by American Society for Microbiology, http://www.asm.org/index.php/asm-newsroom2/88-news-room/journal-tipsheets/91691-new-agent-inhibits-hcv-replication-in-mouse-models-no-resistance-seen)
    (Selected in 'Highlights' section in the journal 'Microbe 2013, Vol. 8, No. 6, Page 241')

1 Protocol published
Colony Forming Assay for HCV-Replicon Cell Line
Authors:  Chang Ho Lee and Seong-Wook Lee, date: 12/20/2013, view: 5333, Q&A: 0
Hepatitis C virus (HCV) is the main causative agent of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Since the HCV genome is present exclusively in RNA form during replication, a number of anti-HCV drugs show appearance of rapid ...
4 Protocols reviewed
Primer Extension Reactions for the PCR- based α- complementation Assay
Authors:  Vasudevan Achuthan and Jeffrey J. DeStefano, date: 06/20/2015, view: 4479, Q&A: 0
The PCR- based- α- complementation assay is an effective technique to measure the fidelity of polymerases, especially RNA-dependent RNA polymerases (RDRP) and Reverse Transcriptases (RT). It has been successfully employed to determine the fidelity ...
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Mismatched Primer Extension Assays
Authors:  Vasudevan Achuthan and Jeffrey J. DeStefano, date: 06/20/2015, view: 3459, Q&A: 0
Steady state kinetic assays have been a reliable way to estimate fidelity of several polymerases (Menendez-Arias, 2009; Rezende and Prasad, 2004; Svarovskaia et al., 2003). The ability to analyze the extension of primers with specific ...
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