Martin Blum Institute of Zoology, University of Hohenheim, Germany
1 protocol

Thomas Thumberger
  • Centre for Organismal Studies (COS), Heidelberg University, Germany
  • 1 Author merit


Ph.D. in Biology, University of Hohenheim, 2011

Current position

Postdoctoral researcher, Centre for Organismal Studies (COS), Heidelberg University, Heidelberg, Germany


  1. Hagenlocher, C., Walentek, P., C, M. L., Thumberger, T. and Feistel, K. (2013). Ciliogenesis and cerebrospinal fluid flow in the developing Xenopus brain are regulated by foxj1. Cilia 2(1): 12.
  2. Hockendorf, B., Thumberger, T. and Wittbrodt, J. (2012). Quantitative analysis of embryogenesis: a perspective for light sheet microscopy. Dev Cell 23(6): 1111-1120.
  3. Thumberger, T., Hagenlocher, C., Tisler, M., Beyer, T., Tietze, N., Schweickert, A., Feistel, K. and Blum, M. (2012). Ciliary and non-ciliary expression and function of PACRG during vertebrate development. Cilia 1(1): 13.
  4. Walentek, P., Beyer, T., Thumberger, T., Schweickert, A. and Blum, M. (2012). ATP4a is required for Wnt-dependent Foxj1 expression and leftward flow in Xenopus left-right development. Cell Rep 1(5): 516-527
  5. Beyer, T., Thumberger, T., Schweickert, A. and Blum, M. (2012). Connexin26-mediated transfer of laterality cues in Xenopus. Biol Open 1(5): 473-481.
  6. Beyer, T., Danilchik, M., Thumberger, T., Vick, P., Tisler, M., Schneider, I., Bogusch, S., Andre, P., Ulmer, B., Walentek, P.*, Niesler, B.*, Blum, M.* and Schweickert, A.* (2012). Serotonin signaling is required for Wnt-dependent GRP specification and leftward flow in Xenopus. Curr Biol 22(1): 33-39.
    = authors contributed equally (alphabetical order)
  7. Schweickert, A., Walentek, P., Thumberger, T. and Danilchik, M. (2012). Linking early determinants and cilia-driven leftward flow in left-right axis specification of Xenopus laevis: a theoretical approach. Differentiation 83(2): S67-77.
  8. Schweickert, A., Vick, P., Getwan, M., Weber, T., Schneider, I., Eberhardt, M., Beyer, T., Pachur, A. and Blum, M. (2010). The nodal inhibitor Coco is a critical target of leftward flow in Xenopus. Curr Biol 20(8): 738-743.
  9. Maisonneuve, C., Guilleret, I., Vick, P., Weber, T., Andre, P., Beyer, T., Blum, M. and Constam, D. B. (2009). Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow. Development 136(17): 3019-3030.
  10. Vick, P., Schweickert, A., Weber, T., Eberhardt, M., Mencl, S., Shcherbakov, D., Beyer, T. and Blum, M. (2009). Flow on the right side of the gastrocoel roof plate is dispensable for symmetry breakage in the frog Xenopus laevis. Dev Biol 331(2): 281-291.
  11. Blum, M., Weber, T., Beyer, T. and Vick, P. (2009). Evolution of leftward flow. Semin Cell Dev Biol 20(4): 464-471.
  12. Blum, M., Beyer, T., Weber, T., Vick, P., Andre, P., Bitzer, E. and Schweickert, A. (2009). Xenopus, an ideal model system to study vertebrate left-right asymmetry. Dev Dyn 238(6): 1215-1225.
  13. Schweickert, A., Weber, T., Beyer, T., Vick, P., Bogusch, S., Feistel, K. and Blum, M. (2007). Cilia-driven leftward flow determines laterality in Xenopus. Curr Biol 17(1): 60-66.
1 Protocol published
Acquisition of Leftward Flow in Xenopus laevis
Authors:  Thomas Thumberger and Martin Blum, date: 12/05/2013, view: 6270, Q&A: 0
In Xenopus, the left-right axis is established following an extracellular vectorial leftward flow driven by monocilia at the gastrocoel roof plate (GRP) during late gastrulation / neurulation (Schweickert et al., 2007). As the GRP ...
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