Hester Bootsma Laboratory of Pediatric Infectious Diseases, Radboud University Medical Centre, The Netherlands
2 protocols
Alka Mehra Institute of Genomics and Integrative Biology
40 protocols

Dennis Nürnberg Freie Universität Berlin
48 protocols

Prashanth Suravajhala Amrita University, Kollam
21 protocols

Shyam Solanki Washington State University
16 protocols

Stefan P.W. de de Vries
  • Radboud University Medical Centre
Research focus
  • Microbiology
  • 2 Author merit


Ph.D., Laboratory of Pediatric Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands

Current position

Research associate, Bacterial Infection Group, Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom


  1. Riesle, S., de Vries, S., Stubbs, S., Amponsah-Mensah, K., Cunningham, A. A., Wood, J., & Sargan, D. (2016). The complete mitochondrial genome of Epomophorus gambianus (Chiroptera: Pteropodidae) and its phylogenetic analysis. Mitochondrial DNA Part B: Resources
  2. Earl, J. P.*, de Vries, S. P.*, Ahmed, A., Powell, E., Schultz, M. P., Hermans, P. W., Hill, D. J., Zhou, Z., Constantinidou, C. I., Hu, F. Z., Bootsma, H. J. and Ehrlich, G. D. (2016). Comparative Genomic Analyses of the Moraxella catarrhalis Serosensitive and Seroresistant Lineages Demonstrate Their Independent Evolution. Genome Biol Evol 8(4): 955-974. *Contribute equally to this work
  3. de Vries, S. P., Gupta, S., Baig, A., L'Heureux, J., Pont, E., Wolanska, D. P., Maskell, D. J. and Grant, A. J. (2015). Motility defects in Campylobacter jejuni defined gene deletion mutants caused by second-site mutations. Microbiology 161(12): 2316-2327.
  4. de Vries, S. P. and Bootsma, H. J. (2014). Differential gene expression of Moraxella catarrhalis upon exposure to human serum. Genom Data 2: 312-313.
  5. Mobegi, F. M., van Hijum, S. A., Burghout, P., Bootsma, H. J., de Vries, S. P., van der Gaast-de Jongh, C. E., Simonetti, E., Langereis, J. D., Hermans, P. W., de Jonge, M. I. and Zomer, A. (2014). From microbial gene essentiality to novel antimicrobial drug targets. BMC Genomics 15: 958.
  6. de Vries, S. P., Rademakers, R. J., van der Gaast-de Jongh, C. E., Eleveld, M. J., Hermans, P. W. and Bootsma, H. J. (2014). Deciphering the genetic basis of Moraxella catarrhalis complement resistance: a critical role for the disulphide bond formation system. Mol Microbiol 91(3): 522-537.
  7. de Vries, S. P., Eleveld, M. J., Hermans, P. W. and Bootsma, H. J. (2013). Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells. PLoS One 8(8): e72193.
  8. de Vries, S. P., Burghout, P., Langereis, J. D., Zomer, A., Hermans, P. W. and Bootsma, H. J. (2013). Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions. Mol Microbiol 87(1): 14-29.
  9. Zomer, A.*, de Vries, S. P.*, Riesbeck, K., Meinke, A. L., Hermans, P. W. and Bootsma, H. J. (2012). Genome sequence of Moraxella catarrhalis RH4, an isolate of seroresistant lineage. J Bacteriol 194(24): 6969. *Contribute equally to this work
  10. Langereis, J. D., Stol, K., Schweda, E. K., Twelkmeyer, B., Bootsma, H. J., de Vries, S. P., Burghout, P., Diavatopoulos, D. A. and Hermans, P. W. (2012). Modified lipooligosaccharide structure protects nontypeable Haemophilus influenzae from IgM-mediated complement killing in experimental otitis media. MBio 3(4): e00079-00012.
  11. Davie, J. J., Earl, J., de Vries, S. P., Ahmed, A., Hu, F. Z., Bootsma, H. J., Stol, K., Hermans, P. W., Wadowsky, R. M., Ehrlich, G. D., Hays, J. P. and Campagnari, A. A. (2011). Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates. BMC Genomics 12: 70.
  12. Schaar, V., de Vries, S. P., Perez Vidakovics, M. L., Bootsma, H. J., Larsson, L., Hermans, P. W., Bjartell, A., Morgelin, M. and Riesbeck, K. (2011). Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells. Cell Microbiol 13(3): 432-449.
  13. de Vries, S. P., van Hijum, S. A., Schueler, W., Riesbeck, K., Hays, J. P., Hermans, P. W. and Bootsma, H. J. (2010). Genome analysis of Moraxella catarrhalis strain BBH18: a human respiratory tract pathogen. J Bacteriol 192(14): 3574-3583.
  14. de Vries, S. P., Bootsma, H. J., Hays, J. P. and Hermans, P. W. (2009). Molecular aspects of Moraxella catarrhalis pathogenesis. Microbiol Mol Biol Rev 73(3): 389-406.
2 Protocols published
Authors:  Stefan P.W. de Vries and Hester J. Bootsma, date: 11/05/2013, view: 7773, Q&A: 0
Phenotypes observed for certain Moraxella catarrhalis wild-type strains or mutants may be caused by a variety of factors including alteration of outer membrane protein composition. Examination of the outer membrane protein profiles may be a ...
Authors:  Stefan P.W. de Vries and Hester J. Bootsma, date: 11/05/2013, view: 8155, Q&A: 0
Moraxella catarrhalis is a human-restricted pathogen that is responsible for respiratory tract infections such as childhood otitis media (OM) and exacerbation of chronic obstructive pulmonary disease (COPD) in adults. Successful ...
2 Protocols reviewed
A Modified Low-quantity RNA-Seq Method for Microbial Community and Diversity Analysis Using Small Subunit Ribosomal RNA
Authors:  Yong-Wei Yan, Ting Zhu, Bin Zou and Zhe-Xue Quan, date: 05/05/2018, view: 3782, Q&A: 0
We propose a modified RNA-Seq method for small subunit ribosomal RNA (SSU rRNA)-based microbial community analysis that depends on the direct ligation of a 5’ adaptor to RNA before reverse-transcription. The method requires only a low-input quantity ...
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Quantifying Symmetrically Methylated H4R3 on the Kaposi’s Sarcoma-associated Herpesvirus (KSHV) Genome by ChIP-Seq
Authors:  Roxanne C. Strahan, Kayla S. Hiura and Subhash C. Verma, date: 03/20/2018, view: 5387, Q&A: 0
Post-translational modifications to histone tails contribute to the three-dimensional structure of chromatin and play an important role in determining the relative expression of nearby genes. One such modification is symmetric di-methylation of ...
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