Jeffrey Tyner Cell, Developmental and Cancer Biology Department, Oregon Health and Science University, USA
2 protocols

Vincent T. Bicocca
  • Hematology and Medical Oncology, Oregon Health and Science University, USA
  • 2 Author merit

Education

Ph.D. in Cell & Develop Biology, Oregon Health & Science University, 2012

Current position

Postdoctoral Researcher, Molecular Genetics, University of Oregon

Publications

Research papers

  1. Bicocca, V. T., Chang, B. H., Masouleh, B. K., Muschen, M., Loriaux, M. M., Druker, B. J. and Tyner, J. W. (2012). Crosstalk between ROR1 and the Pre-B cell receptor promotes survival of t(1;19) acute lymphoblastic leukemia. Cancer Cell 22(5): 656-667.
  2. Tomilov, A. A., Bicocca, V., Schoenfeld, R. A., Giorgio, M., Migliaccio, E., Ramsey, J. J., Hagopian, K., Pelicci, P. G. and Cortopassi, G. A. (2010). Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice. J Biol Chem 285(2): 1153-1165.
  3. Spence, K. O., Bicocca, V. T. and Rosenheim, J. A. (2007). Friend or foe?: a plant's induced response to an omnivore. Environ Entomol 36(3): 623-630.
  4. Stork, J. R., Rios, D., Pham, D., Bicocca, V., Olmstead, M. M. and Balch, A. L. (2005). Metal-metal interactions in platinum(II)/gold(I) or platinum(II)/silver(I) salts containing planar cations and linear anions. Inorg Chem 44(10): 3466-3472.

Abstracts

  1. Bicocca, V.T., Chang, B.H., Muschen, M., Loriaux, M.M., Druker, B.J., and J.W. Tyner. (2011). Compensatory Signaling from ROR1 and the Pre-B Cell Receptor Promote Survival of t(1;19) Acute Lymphoblastic Leukemia. Abstract in Blood 118 (21): 1057.
  2. Bicocca, V.T., Chang, B.H., Muschen, M., Loriaux, M.M., Druker, B.J., and J.W. Tyner. (2010). ROR1 as a Therapeutic Target in E2A-PBX1-Positive Acute Lymphoblastic Leukemia. Abstract in Blood 116 (21): 240.
  3. Tyner, J.W., Loriaux, M.M., Willis, S.G., Chang, B.H., Bicocca, V., Oh, S., Hollink, I., Segers, S., den Boer, M., Heuvel-Eibrink, M., Zwaan, C.M., Gotlib, J.R. Deininger, M.W., and B.J. Druker. (2009). RAPID siRNA Screen for Identification of Therapeutic Gene Targets in Patients with Hematologic Malignancies. Abstract in Blood, 114 (22): 1529.
  4. Tyner, J.W., Loriaux, M.M., Willis, S.G., Chang, B.H., Bicocca, V., Oh, S., Hollink, I., Segers, S., den Boer, M., Zwaan, C.M., Gotlib, J.R. Deininger, M.W., and B.J. Druker. (2008). RNAi Screening of the Tyrosine Kinome Identifies Therapeutic Targets in Leukemia Patients. Abstract in Blood, 112 (11): 281.
  5. O'Hare, T., Mousses, S., Shanmugam, K., Bicocca, V. T., Eide, C. A., Jacob, J., Williamson, T., Shannon, P., MacArthur, R. B. and Weitman, S. (2007). A new class of thienopyrimidine Src inhibitors demonstrates potent growth suppression of imatinib resistant Ba/F3 cells harboring a wide range of BCR-ABL mutations, including the CML relevant T315I. AACR Meeting Abstract, B238.
2 Protocols published
ROR1 Flow Cytometry
Authors:  Vincent T. Bicocca and Jeffrey W. Tyner, date: 09/20/2013, view: 4153, Q&A: 0
ROR1 is a receptor tyrosine kinase family member studied for its roles in development and cancer. Here we describe a protocol for analysis of ROR1 surface expression in acute lymphoblastic leukemia immortalized cell lines by flow cytometry.
Immunoprecipitation of ROR1
Authors:  Vincent T. Bicocca and Jeffrey W. Tyner, date: 09/20/2013, view: 4063, Q&A: 0
ROR1 is a receptor tyrosine kinase family member studied for its roles in development and cancer. Here we describe a protocol for immunoprecipitation of endogenous ROR1 from t(1;19) (a disease subtype categorized by its chromosome translocation) ...
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