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Coauthors
Benita Westerlund-Wikström Department of Biosciences, University of Helsinki, Finland
1 protocol
Coreviewers
Agnès Groisillier Sorbonne Universités, University Pierre and Marie Curie
2 protocols

Alba Blesa Universidad Francisco de Vitoria
3 protocols

Arsalan Daudi University of California
153 protocols

Darrell Cockburn Pennsylvania State University
3 protocols

Reviewer
Timo A Lehti
  • Post-Doc, University of Helsinki
Research focus
  • Microbiology
  • 1 Author merit

Education

Ph.D., University of Helsinki

Publications

Uotila LM, Guenther C, Savinko T, Lehti TA & Fagerholm SC (2017) Filamin A regulates neutrophil adhesion, production of reactive oxygen species and neutrophil extracellular trap release. The Journal of Immunology 199: 3644-3653.

Skog MS, Nystedt J, Korhonen M, Anderson H, Lehti TA, Pajunen MI & Finne J (2016) Expression of neural cell adhesion molecule and polysialic acid in human bone marrow-derived mesenchymal stromal cells. Stem Cell Research & Therapy 7: 113.

Lehti TA, Bauchart P, Kukkonen M, Dobrindt U, Korhonen T, & Westerlund-Wikström B (2013) Phylogenetic Group –Associated Differences in Regulation of the Common Colonization Factor Mat Fimbria in Escherichia coli. Molecular Microbiology 87(6): 1200-1222.

Lehti TA, Bauchart P, Dobrindt U, Korhonen T, & Westerlund-Wikström B (2012) The fimbriae activator MatA switches off motility in Escherichia coli by repression of the flagellar master operon flhDC. Microbiology 158(6): 1444-1455.

Lehti TA, Heikkinen J, Korhonen T, & Westerlund-Wikström B (2012) The response regulator RcsB activates expression of Mat fimbriae in meningitic Escherichia coli. Journal of Bacteriology 194(13): 3475-3485.

Edelman S, Lehti TA, Kainulainen V, Antikainen J, Kylväjä S, Baumann M, Westerlund-Wikström B & Korhonen T (2012) Identification of a high-molecular-weight Lactobacillus Epithelium Adhesin (LEA) of Lactobacillus crispatus ST1 that binds to stratified squamous epithelium. Microbiology 158(Pt 7): 1713-1722.

Lehti TA, Bauchart P, Heikkinen J, Hacker J, Korhonen T, Dobrindt U & Westerlund-Wikström B (2010) Mat fimbriae promote biofilm formation by meningitis-associated Escherichia coli. Microbiology 156(8): 2408-2417.

1 Protocol published
Colony Immunoblotting Assay for Detection of Bacterial Cell-surface or Extracellular Proteins
Authors:  Timo A. Lehti and Benita Westerlund-Wikström, date: 09/05/2013, view: 11732, Q&A: 1
This simple protocol describes how to detect antigens from agar-grown bacterial colonies transferred to nitrocellulose using specific antibodies. The protocol is well suitable for detection of bacterial proteins exposed on the cell surface or ...
8 Protocols reviewed
Live-cell Imaging of Neisseria meningitidis Microcolony Dispersal Induced by Lactate or Other Molecules
Authors:  Sara Sigurlásdóttir, Olaspers Sara Eriksson, Jens Eriksson and Ann-Beth Jonsson, date: 01/20/2018, view: 206, Q&A: 0
To efficiently colonize the nasopharyngeal epithelium, the human restricted pathogen Neisseria meningitidis follows a multistep adhesion cascade. First, the bacteria adhere to host cells and aggregate into spherical shaped structures called ...
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Markerless Gene Editing in the Hyperthermophilic Archaeon Thermococcus kodakarensis
Authors:  Alexandra M. Gehring, Travis J. Sanders and Thomas J. Santangelo, date: 11/20/2017, view: 692, Q&A: 0
The advent of single cell genomics and the continued use of metagenomic profiling in diverse environments has exponentially increased the known diversity of life. The recovered and assembled genomes predict physiology, consortium interactions and ...
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