Andrea Tenner Molecular Biology and Biochemistry Department, University of California, USA
2 protocols

Marie Benoit Molecular Biology and Biochemistry Department, University of California, USA
2 protocols
Alka Mehra Institute of Genomics and Integrative Biology
20 protocols

Guillaume Bompard Institut de Génétique Humaine
2 protocols

HongLok Lung University of Hong Kong
58 protocols

Jia Li SRI International
50 protocols

Reviewer
Elizabeth V. Clarke
  • Research associate, Center for Health Research-Kaiser Permanente
Research focus
  • Genetics
  • Genetic Epidemiology, Biobanking, Cancer, Preventative Medicine
  • 2 Author merit

Education

Ph.D., University of California Irvine, 2014

Publications

Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function.
Fonseca MI, Chu S, Pierce AL, Brubaker WD, Hauhart RE, Mastroeni D, Clarke EV, Rogers J, Atkinson JP, Tenner AJ.
PLoS One. 2016 Feb 25;11(2):e0149792. doi: 10.1371/journal.pone.0149792. eCollection 2016.

Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation.
Clarke EV, Weist BM, Walsh CM, Tenner AJ.
J Leukoc Biol. 2015 Jan;97(1):147-60. doi: 10.1189/jlb.3A0614-278R. Epub 2014 Nov 7.

Complement modulation of T cell immune responses during homeostasis and disease.
Clarke EV, Tenner AJ.
J Leukoc Biol. 2014 Nov;96(5):745-56. doi: 10.1189/jlb.3MR0214-109R. Epub 2014 Sep 10. Review.

Purification of Human Monocytes and Lymphocyte Populations by Counter Current Elutriation- A Short Protocol.
Clarke EV, Benoit ME, Tenner AJ.
Bio Protoc. 2013 Dec 5;3(23). pii: e981.

Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers.
Ueno N, Harker KS, Clarke EV, McWhorter FY, Liu WF, Tenner AJ, Lodoen MB.
Cell Microbiol. 2014 Apr;16(4):580-95. doi: 10.1111/cmi.12239. Epub 2013 Dec 4.

C1q Binding to and Uptake of Apoptotic Lymphocytes by Human Monocyte-derived Macrophages.
Benoit ME, Clarke EV, Tenner AJ.
Bio Protoc. 2013 Sep 5;3(17). pii: e877.

Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.
Benoit ME, Clarke EV, Morgado P, Fraser DA, Tenner AJ.
J Immunol. 2012 Jun 1;188(11):5682-93. doi: 10.4049/jimmunol.1103760. Epub 2012 Apr 20.
2 Protocols published
Purification of Human Monocytes and Lymphocyte Populations by Counter Current Elutriation – A Short Protocol
Authors:  Elizabeth V. Clarke, Marie E. Benoit and Andrea J. Tenner, date: 12/05/2013, view: 6421, Q&A: 0
Investigations of the activation processes involved in human monocytes and monocyte-derived macrophages and dendritic cells often required large numbers of cells that have not been possibly altered or activated by adherence to surfaces, by binding ...
C1q Binding to and Uptake of Apoptotic Lymphocytes by Human Monocyte-derived Macrophages
Authors:  Marie E. Benoit, Elizabeth V. Clarke and Andrea J. Tenner, date: 09/05/2013, view: 4990, Q&A: 0
To characterize macrophage gene expression profiles during the uptake of autologous apoptotic cells, we developed a unique, more physiologic system using primary human monocyte derived macrophages purified via a nonactivating isolation procedure ...
6 Protocols reviewed
Generation of IgG-Fc Glycovariants Using Recombinant Glycosidases and Glycosyltransferases
Authors:  Isaak Quast, Michael A. Maurer and Jan D. Lünemann, date: 08/05/2016, view: 5085, Q&A: 0
The immunoglobulin G (IgG) fragment crystallizable (Fc) domain contains a single, highly conserved asparagine 297 (N297) glycosylation site in the CH2 domain, which is buried within the hydrophobic core of each of the two heavy chains. The ...
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Measurement of TACE Activity in Extracts from Cultured Cells
Authors:  Xiuling Xu, Mabel T. Padilla and Yong Lin, date: 10/20/2014, view: 4841, Q&A: 0
In cigarette smoke–induced and inflammation-associated lung cancer development, cigarette smoke extract (CSE) activates tumor necrosis factor-alpha (TNF-α) secretion from macrophages. TNF-α converting enzyme (TACE), also known as α-Secretase or ...
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