Jeffrey Perry Internal Medicine, University of Michigan, United States of American
2 protocols

Mariam Gonzalez-Hernandez Department of Microbiology and Immunology, Graduate Program of Immunology, University of Michigan, USA
1 protocol

Christiane E. Wobus
  • Department of Microbiology and Immunology, University of Michigan, USA
Research focus
  • Microbiology
  • 1 Author merit


Ph.D. in Virology, University of Heidelberg, Germany, 2000

Current position

Assistant professor Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI.


  1. Nelson, A. M., Elftman, M. D., Pinto, A. K., Baldridge, M., Hooper, P., Kuczynski, J., Petrosino, J. F., Young, V. B. and Wobus, C. E. (2013). Murine norovirus infection does not cause major disruptions in the murine intestinal microbiota. Microbiome 1(1): 7.
  2. Nelson, A. M., Walk, S. T., Taube, S., Taniuchi, M., Houpt, E. R., Wobus, C. E. and Young, V. B. (2012). Disruption of the human gut microbiota following Norovirus infection. PLoS ONE 7(10): e48224.
  3. Gonzalez-Hernandez, M. B., Bragazzi Cunha, J. and Wobus, C. E. (2012). Plaque assay for murine norovirus. J Vis Exp(66): e4297.
  4. Perry, J. W., Ahmed, M., Chang, K. O., Donato, N. J., Showalter, H. D. and Wobus, C. E. (2012). Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response. PLoS Pathog 8(7): e1002783.
  5. Taube, S., Perry, J. W., McGreevy, E., Yetming, K., Perkins, C., Henderson, K. and Wobus, C. E. (2012). Murine noroviruses bind glycolipid and glycoprotein attachment receptors in a strain-dependent manner. J Virol 86(10): 5584-5593.
  6. Burkholder, K. M., Perry, J. W., Wobus, C. E., Donato, N. J., Showalter, H. D., Kapuria, V. and O'Riordan, M. X. (2011). A small molecule deubiquitinase inhibitor increases localization of inducible nitric oxide synthase to the macrophage phagosome and enhances bacterial killing. Infect Immun 79(12): 4850-4857.
  7. Kim, Y. G., Park, J. H., Reimer, T., Baker, D. P., Kawai, T., Kumar, H., Akira, S., Wobus, C. and Nunez, G. (2011). Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections. Cell Host Microbe 9(6): 496-507.
  8. Higgins, P. D., Johnson, L. A., Sauder, K., Moons, D., Blanco, L., Taube, S. and Wobus, C. E. (2011). Transient or persistent norovirus infection does not alter the pathology of Salmonella typhimurium induced intestinal inflammation and fibrosis in mice. Comp Immunol Microbiol Infect Dis 34(3): 247-257.
1 Protocol published
Neutral Red Assay for Murine Norovirus Replication and Detection in a Mouse
Neutral red (NR) is a dye that must be actively imported into the cell, and, therefore, the dye has been used for decades to selectively stain living cells. In addition, NR can also be incorporated into virus particles, although the mechanism ...
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