Immunology

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    Protocols in Current Issue
    In vitro Inflammasome Assay
    Authors:  Mario M. Zaiss and Kendle M. Maslowski, date: 06/05/2014, view: 11588, Q&A: 0
    [Abstract] Innate immune cells sense pathogen and danger-associated molecular patterns (PAMPs and DAMPs) through a range of innate immune pattern recognition receptors (PRRs). One type of PRRs are the Nod-like receptors (NLRs), which form inflammasomes; a molecular platform required for the recruitment and activation of Caspase-1, which in turn cleaves and ...



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