Surgical Induction of Endometriosis in Female Mice
[Abstract] Endometriosis is a common gynecological disease characterized by the presence of endometrial tissue outside the uterine cavity. It is frequently associated with pain, infertility and a reduced quality of life, and it lacks adequate treatment. Several rodent models of endometriosis have been developed through heterologous and homologous ...
Vascular Permeability Assay in Human Coronary and Mouse Brachiocephalic Arteries
Authors: Liang Guo,
Raquel Fernandez,
Atsushi Sakamoto,
Anne Cornelissen,
Ka Hyun Paek,
Parker J. Lee,
Leah M. Weinstein,
Carlos J. Collado-Rivera,
Emanuel Harari,
Robert Kutys,
Torie S. Samuda,
Nicole A. Singer,
Matthew D. Kutyna,
Frank D. Kolodgie,
Renu Virmani and
Aloke V. Finn,
date: 10/20/2018,
view: 3988,
Q&A: 0
[Abstract] Coronary artery disease remains an important cause of morbidity and mortality. Previous work, including ours, has focused on the role of intraplaque hemorrhage, particularly from immature microvessel angiogenesis, as an important contributor to plaque progression via increases in vascular permeability leading to further intraplaque hemorrhage, ...
Artificial Inhalation Protocol in Adult Mice
Authors: Thomas P. Eiting and
Matt Wachowiak,
date: 09/20/2018,
view: 3280,
Q&A: 0
[Abstract] Research in the area of in vivo olfactory physiology benefits from having direct access to the nasal airways through which odorants can be presented. Ordinarily, the passage of odorants through the airways is controlled by respiratory rhythm. This fact makes it difficult to control the timing and strength of an olfactory stimulus, since ...
Hyaluronan Isolation from Mouse Mammary Gland
Authors: Cornelia Tolg,
Mary Cowman and
Eva A. Turley,
date: 06/05/2018,
view: 3438,
Q&A: 0
[Abstract] The glycosaminoglycan hyaluronan (HA) is a key component of the extracellular matrix. The molecular weight of HA is heterogeneous and can reach from several million to several hundred daltons. The effect of HA on cell behavior is size dependent; fragmented HA acts as a danger signal, stimulates cell migration and proliferation and is ...