Education

Ph.D in Immunology, Department of Immunology, Soochow University, 2009.
M.D in Pediatrics, Department of Neurology, Children’s Hospital, Soochow University, 2005

Current position

Associate Professor in Pediatric Neurology, Department of Neurology, Children’s Hospital, Soochow University

Publications (since 2009)

1. Chen, C., Shen, Y., Qu, Q. X., Chen, X. Q., Zhang, X. G. and Huang, J. A. (2013). Induced expression of B7-H3 on the lung cancer cells and macrophages suppresses T-cell mediating anti-tumor immune response. Exp Cell Res 319(1): 96-102. [Epub ahead of print] (IF 3.58)
   
2. Yan, R., Yang, S., Sun, J., Chen, X., Zhang, G., Feng, P. and Zhang, X. (2012). A novel monoclonal antibody against mouse B7-H3 developed in rats. Hybridoma 31(4): 267-271. (IF 0.417)
   
3. BAI, Y.-h., CHEN, X.-q.*, WANG, Z.-d., LI, Y., CUI, W.-l., ZHANG, G.-b. and XUE, J. (2012). Changes of B7-H3 and Interleukin-1β Levels in Cerebrospinal Fluid and Serum in Children with Bacterial Meningitis and It′ s Clinical Significance. Journal of Applied Clinical Pediatrics 12: 012. (* Corresponding Author)
   
4. CHEN, X.-q., WANG, J.-h., ZHANG, X.-g. and BAO, G.-s. (2012). B7 Homolog 3 Promote Inflammatory Response and Pathological Injury of Streptococcus Pneumoniae Meningitis via A Toll-Like Receptor 2 Dependent Mechanism in Mice. Journal of Applied Clinical Pediatrics 17: 020.
   
5. Chen, X., Quinn, E. M., Ni, H., Wang, J., Blankson, S., Redmond, H. P., Wang, J. H. and Feng, X. (2012). B7-H3 participates in the development of experimental pneumococcal meningitis by augmentation of the inflammatory response via a TLR2-dependent mechanism. J Immunol 189(1): 347-355. ( IF 5.78)
   
6. Chen, X., Bai, Y., Cui, W., Wang, Z., Zhang, G., Xu, Y., Zhu, X., Li, Y. and Wang, J. H. (2013). Effects of B7-H3 on the Inflammatory Response and Expression of MMP-9 in Mice with Pneumococcal Meningitis. J Mol Neurosci 50(1): 146-153 [Epub ahead of print] ( IF 2.50)
   
7. Bao, G. S., Cheng, X. Q., Hua, Y., Wang, Z. D. and Liu, Z. G. (2011). Changes of glucocorticoid receptor mRNA expression in basolateral amygdale-kindled rats. Chin Med J (Engl) 124(17): 2622-2627.( IF 0.95,Co-first author)
   
8. Chen, X., Zhang, G., Li, Y., Feng, X., Wan, F., Zhang, L., Wang, J. and Zhang, X. (2009). Circulating B7-H3(CD276) elevations in cerebrospinal fluid and plasma of children with bacterial meningitis. J Mol Neurosci 37(1): 86-94. (IF 2.70)
   
9. Chen, X., Bao, G., Hua, Y., Li, Y., Wang, Z. and Zhang, X. (2009). The effects of topiramate on caspase-3 expression in hippocampus of basolateral amygdala (BLA) electrical kindled epilepsy rat. J Mol Neurosci 38(2): 201-206. (SCI included, IF 2.70)