LL
Reviewer
Lip Nam LOH
  • Research scientist, Lytica Therapeutics
Research fields
  • Cell Biology, Microbiology
Personal information

Education

PhD, London School of Hygiene and Tropical Medicine, 2012

Publications

Hanachi, P., Loh, L.N., Fauziah, O., Rafiuz, Z.H., Tee, S.T., Lye, C.W., and Lam, T.P. 2004. The effect of neem (Azadirachta indica) extract and dietary selenium on distribution of selenium in hepatocarcinogenesis induced rat. Medical Journal of Malaysia 59(B):208-209.

Mortazavi, P.N., Keisary, E., Loh, L.N., Jung, S-Y, and Khan, N.A. 2011. Possible roles of phospholipase A2 in the biological activities of Acanthamoeba castellanii (T4 genotype). Protist 162:168-176.

Loh, L.N., and Ward, T.H. 2012. Escherichia coli K1 invasion of human brain microvascular endothelial cells. In Methods Enzymol, Conn, P.M. (ed.). Academic Press, pp. 93-113.

Gratz, N.*, Loh, L.N.*, and Tuomanen, E. Pneumococcal translocation: development of bacteremia and meningitis. In Streptococcus pneumonia: Molecular mechanisms of host-pathogen interactions, Hammerschmidt, S., Brown, J., and Orihuela, C. (ed.). Elsevier.
*equal authorship

Humann, J., Mann, B., Gao, G., Moresco, P., Ramahi, J., Loh, L.N., Farr, A., Hu, Y., Durick-Eder, K., Fillon, S.A., Smeyne, R., and Tuomanen, E.I. 2016. Bacterial peptidoglycan traverses the placenta to induce fetal neuroproliferation and aberrant postnatal behavior. Cell Host and Microbe 19:388-399.

Kamei, A., Gao, G., Neale, G., Loh, L.N., Vogel, P., Thomas, P.G., Tuomanen, E.I., and Murray, P.J. 2016. Exogenous remodelling of the lung macrophage microenvironment protects against infectious consequences of bone marrow ablative chemotherapy. Proc Natl Acad Sci U S A 113:E6153-E6161.

Mann, B., Loh, L.N., Gao, G., and Tuomanen E.I. 2016. Preparation of purified bacterial cell wall and detection in placenta and fetal tissues. Bio-protocol 6:e2037.

Loh, L.N., Gao, G., and Tuomanen, E. 2017. Dissecting bacterial cell wall entry and signalling in eukaryotic cells: an actin-dependent pathway parallels platelet activating factor receptor-mediated endocytosis. mBio 8:e02030-16.

Loh, L.N., McCarthy, E.M.C., Narang, P., Khan, N.A., and Ward, T.H. 2017. Escherichia coli K1 utilises host macropinocytic pathways for invasion of brain microvascular endothelial cells. Traffic 18:733-746.

Gratz, N., Loh, L.N., Mann, B., Gao, G., Carter, R., Rosch, J., and Tuomanen, E.I. 2017. Pneumococcal neuraminidase activates TGF-β signalling. Microbiology 163:1198-1207.

Kao, C., Goymer, J., Loh, L.N., Mahant, A., Burn, C., and Herold, B.C. 2020. Murine model of maternal immunization demonstrates roles for maternal Fc receptor activating and neutralizing antibodies in protecting neonates from Herpes Simplex virus infections. Journal of Infectious Diseases 221:729-738.

Ramsey, N.L.M., Visciano, M., Hunte, R., Loh, L.N., Burn Aschner, C., Jacobs, W.R. Jr., and Herold, B.C. 2020. A single-cycle glycoprotein D deletion viral vaccine candidate, ∆gD-2, elicits polyfunctional antibodies that protect against ocular Herpes Simplex Virus (HSV). Virology 94:e00335-20.

Rastogi, D., Johnston, A.D., Nico, J., Loh, L.N., Jorge, Y., Suzuki, M., Macian, F., and Greally, J.M. 2020. Functional genomics of the pediatric obese asthma phenotype reveal enrichment of Rho-GTPase pathways. Am. J. Respir. Crit. Care Med. 202:259-274.

Burn Aschner, C., Loh, L.N., Knipe, D., Ware, C.F., Jacobs Jr., W.R., and Herold, B.C. Herpes Simplex Virus (HSV) glycoprotein D restricts effective vaccination by suppressing LIGHT-HVEM pathway. Science Immunology 5:eaax2454.
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