Thank you for agreeing to share summary data with MR-Base.
Please could you provide the following summary data for each SNP:
1. Regression coefficient for each SNP
2. Standard error for the regression coefficient
3. Effect allele (i.e. the coded allele)
4. Non-effect allele
5. Effect allele frequency
The following metrics of genotype quality would also be helpful if available:
6. P values for Hardy–Weinberg equilibrium
7. P values / Cochran's Q test for between study heterogeneity
8. Metrics of SNP imputation quality, such as info / r2 scores (for imputed SNPs)
We are also seeking the following information (please provide as much as possible):
9. A PubMed identifier (PMID) for a paper we can use as a reference for the methods used to produce the summary data
10. Confirmation that the summary data have been through the same post-GWAS filtering / quality control procedures described in the published paper
11. Sample size or number of cases and controls in the GWAS analysis
12. Genome build and reference strand
13. Geographic origins for study participants (e.g. East Asian, European, etc)
Do you have any questions about this protocol?
Post your question to gather feedback from the community. We will also invite the authors of this
article to respond.