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Validation and Survival Analysis of Hub Genes

YW Yanan Wang
JG Jiguang Guo

Last updated date: Jul 10, 2022 Views: 528 Forks: 0

original An abbreviated version of this protocol was published in Frontiers in Molecular Biosciences in Mar, 2022
Identification of Down-Regulated ADH1C is Associated With Poor Prognosis in Colorectal Cancer Using Bioinformatics Analysis
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The 15 hub genes were first input into the GEPIA website (http://gepia.cancer-pku.cn/detail.php?gene=&clicktag=boxplot) for validation. You should input the gene symbol and choose the dataset you interested in. We used the |Log2FC|>1 and p<0.05 as the cutoff values. We also chose the cancer type and input the gene name into the OncoLnc website (http://www.oncolnc.org/cancer/). The results can be directly download from the websites.

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How to cite：
Readers should cite both the Bio-protocol preprint and the original research article where this protocol was used:
  1. Wang, Y and Guo, J(2022). Validation and Survival Analysis of Hub Genes. Bio-protocol Preprint. bio-protocol.org/prep1783.
  2. Li, M., Liu, Z., Song, J., Wang, T., Wang, H., Wang, Y. and Guo, J.(2022). Identification of Down-Regulated ADH1C is Associated With Poor Prognosis in Colorectal Cancer Using Bioinformatics Analysis. Frontiers in Molecular Biosciences 0(0). DOI: 10.3389/fmolb.2022.791249

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