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Preprint

Statistical analysis

RZ Ramona A.J. Zwamborn
JV Jan H. Veldink

Last updated date: Apr 20, 2022 Views: 602 Forks: 0

original An abbreviated version of this protocol was published in Science Translational Medicine in Feb, 2022
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS
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Dear Sultana Solaiman, 

 

Thank you for your interest in our research. For a protocol of our analyses we would like to refer you to our github: https://github.com/pjhop/EWAS_MinE. Here you will find all the template scripts used for this publication. Please don't hesitate to contact Ramona Zwamborn or Paul Hop for further questions regarding the scripts (r.a.j.zwamborn-3@umcutrecht.nl; p.j.hop-2@umcutrecht.nl). 

Good luck with the analyses! 

 

On behalf of Jan, 

Paul & Ramona 

  

Copyright: Content may be subjected to copyright.
How to cite：
Readers should cite both the Bio-protocol preprint and the original research article where this protocol was used:
  1. Zwamborn, R and Veldink, J(2022). Statistical analysis. Bio-protocol Preprint. bio-protocol.org/prep1628.
  2. Hop, P. J., Zwamborn, R. A., Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van Rheenen, W., van Vugt, J. J., Dekker, A. M., Westeneng, H., Tazelaar, G. H., van Eijk, K. R., Moisse, M., Baird, D., Al Khleifat, A., Iacoangeli, A., Ticozzi, N., Ratti, A., Cooper-Knock, J., Morrison, K. E., Shaw, P. J., Basak, A. N., Chiò, A., Calvo, A., Moglia, C., Canosa, A., Brunetti, M., Grassano, M., Gotkine, M., Lerner, Y., Zabari, M., Vourc’h, P., Corcia, P., Couratier, P., Mora Pardina, J. S., Salas, T., Dion, P., Ross, J. P., Henderson, R. D., Mathers, S., McCombe, P. A., Needham, M., Nicholson, G., Rowe, D. B., Pamphlett, R., Mather, K. A., Sachdev, P. S., Furlong, S., Garton, F. C., Henders, A. K., Lin, T., Ngo, S. T., Steyn, F. J., Wallace, L., Williams, K. L., Neto, M. M., Cauchi, R. J., Blair, I. P., Kiernan, M. C., Drory, V., Povedano, M., de Carvalho, M., Pinto, S., Weber, M., Rouleau, G. A., Silani, V., Landers, J. E., Shaw, C. E., Andersen, P. M., McRae, A. F., van Es, M. A., Pasterkamp, R. J., Wray, N. R., McLaughlin, R. L., Hardiman, O., Kenna, K. P., Tsai, E., Runz, H., Al-Chalabi, A., van den Berg, L. H., Van Damme, P., Mill, J. and Veldink, J. H.(2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine 14(633). DOI: 10.1126/scitranslmed.abj0264

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