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Preprint

Mathematical modeling of NF-κB

MS Minjun Son
ST Savaş Tay

Last updated date: Jan 11, 2022 Views: 741 Forks: 0

original An abbreviated version of this protocol was published in Science Signaling
NF-κB responds to absolute differences in cytokine concentrations
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The Matlab code for NF-kB simulation is attached to this protocol. Running "E10_Sim_parent.m' will simulate the different TNF ramping patterns and reproduce the Fig 4 in the main manuscript. 

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zip Sim_for_DoseDifferetiation_by_NFkB.zip download
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How to cite：
Readers should cite both the Bio-protocol preprint and the original research article where this protocol was used:
  1. Son, M and Tay, S(2022). Mathematical modeling of NF-κB. Bio-protocol Preprint. bio-protocol.org/prep1498.
  2. Son, M., Wang, A. G., Tu, H., Metzig, M. O., Patel, P., Husain, K., Lin, J., Murugan, A., Hoffmann, A. and Tay, S.(2021). NF-κB responds to absolute differences in cytokine concentrations . Science Signaling 14(666). DOI: 10.1126/scisignal.aaz4382

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