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Typical withdrawal response in rats.
DOI: 10.21769/BioProtoc.v436 Published: Aug 20, 2017 Views: 7529
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This video clip shows two different withdrawal scenarios of a rat that can occur whilst the animal is in the testing apparatus. The first example shows a proper withdrawal response in which the animal removes its paw from the heat and immediately licks its paw as a reflex. The second example shows removal of the paw from the heat source which is not due to the heat but rather is voluntary movement of the paw. In the second example there is no licking of the paw or acknowledgement of the heat and should therefore not be included as a proper withdrawal response.
Extracted from protocol
Assessment of Thermal Pain Sensation in Rats and Mice Using the Hargreaves Test
Cheah, M., Fawcett, J. W. and Andrews, M. R. (2017). Bio-protocol 7(16): e2506.
DOI: 10.21769/BioProtoc.2506.
This video clip shows two different withdrawal scenarios of a rat that can occur whilst the animal is in the testing apparatus. The first example shows a proper withdrawal response in which the animal removes its paw from the heat and immediately licks its paw as a reflex. The second example shows removal of the paw from the heat source which is not due to the heat but rather is voluntary movement of the paw. In the second example there is no licking of the paw or acknowledgement of the heat and should therefore not be included as a proper withdrawal response.
Extracted from protocol
Assessment of Thermal Pain Sensation in Rats and Mice Using the Hargreaves Test
Cheah, M., Fawcett, J. W. and Andrews, M. R. (2017). Bio-protocol 7(16): e2506.
DOI: 10.21769/BioProtoc.2506.
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Keywords
Thermal pain, Hargreaves, Rats, Mice, Behavioral testing
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