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Showing experimental protocol for the establishment of empathy for pain model in laboratory animals.
DOI: 10.21769/BioProtoc.v228 Published: Jun 20, 2019 Views: 1109
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During Days 1-3, environmental and manipulating adaptation to the experimental environment and manual handling by the experimenters. On Day 4, the baseline values of PWMT in both hind paws of a naive CO rat were first measured and determined using a set of von Frey monofilaments, followed by a VCR of 30-min PDSI between a naïve CO and a familiar conspecific (CD) in pain (for detailed behavioral expressions during 30 min PDSI also see Video 2 that was finally succeeded by last measurement of PWMT for determining whether social pain contagion occurred in the naive CO rats.
Extracted from protocol
Rat Model of Empathy for Pain
Yu, Y., Li, C., Du, R. and Chen, J. (2019). Bio-protocol 9(12): e3266.
DOI: 10.21769/BioProtoc.3266.
During Days 1-3, environmental and manipulating adaptation to the experimental environment and manual handling by the experimenters. On Day 4, the baseline values of PWMT in both hind paws of a naive CO rat were first measured and determined using a set of von Frey monofilaments, followed by a VCR of 30-min PDSI between a naïve CO and a familiar conspecific (CD) in pain (for detailed behavioral expressions during 30 min PDSI also see Video 2 that was finally succeeded by last measurement of PWMT for determining whether social pain contagion occurred in the naive CO rats.
Extracted from protocol
Rat Model of Empathy for Pain
Yu, Y., Li, C., Du, R. and Chen, J. (2019). Bio-protocol 9(12): e3266.
DOI: 10.21769/BioProtoc.3266.
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Keywords
Empathy, Prosocial behavior, Altruism, Pain, Rodent, Model
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