Is there any difference in using "manual" WGCNA vs. using the BlockwiseModules function in terms of the quality of the results?

protocol Protocol: A Protocol for Weighted Gene Co-expression Network Analysis With Module Preservation and Functional Enrichment Analysis for Tumor and Normal Transcriptomic Data

Blockwise modules divides the data and makes the networks separately, does it generate the same quality results as "manual" WGCNA?

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