In which settings do condensate dynamics contribute the most to microscopy?

Condensate dynamics contribute most when studying rapid molecular exchange, fusion/fission events, and phase transitions in live-cell environments using time-lapse fluorescence or FRAP imaging.

They are especially informative in contexts where biochemical reactions are spatially confined (e.g., transcriptional hubs, stress granules, signaling clusters) and where changes in viscosity or material state reflect function.

Microscopy excels when paired with quantitative metrics (recovery curves, droplet coalescence kinetics, morphological changes) to link physical properties with biological outcomes.