I have recently applied this method to two different viral particles....

Protocol: Alphavirus Purification Using Low-speed Spin Centrifugation

I have recently applied this method to two different viral particles. One of them has envelope (~42 nm) and we have run ~24 hours for it. The particles look fine under TEM. If your particles were damaged, you would probably like to check about your buffer or culture media (pH, ionic streng Read more Read less

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