why need to use Matrigel in this experiment? what is the function...

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ngu van trinh
Dec 10, 2018
protocol Protocol: Subcutaneous Injection of Tumor Cells
why need to use Matrigel in this experiment? what is the function of Matrigel? Any research did without Matrigel?
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ngu van trinh Answered Dec 14, 2018

trinh van ngu

Thank you so much for your response.
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shohreh fakhari Answered Dec 11, 2018

kurdistan university of medical sciences

Matrigel has been shown to significantly enhance the tumorigenicity of a wide range of cancer cell lines in vivo.
https://link.springer.com/protocol/10.1385/1-59259-406-9:287
if you don't want to use matrigel, you should use large number of cells for increased tumorigenicity of cancer cells.
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