can we use cd66 as monocytes surface marker?

I personally have no experience with CD66. However, CD66 is expressed by many cell types including monocytes, neutrophils, and epithelial cells. So I am not sure how specific it would be as a monocyte marker. In addition, CD14 and CD16 allow us to distinguish the three subsets of monocytes which are phenotypically and functionally different from each other.

I hope this helps. Thank you for your question.

Zheng Liu