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Sources on substitutes

Charlotte St Aug 14, 2023

I have heard it before but I cannot find any souces on what is the reason for why blood type 0 or guinia pig blood can be used substitutes for bakers yeast when looking at type 1 fimbrea?

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Beata Sobieszczańska Author Answered Aug 20, 2023

Medical University Wrocław, Poland

Dear Charlotte,

Type 1 fimbria binds to mannose-containing receptors (mannosylated glycoproteins) which are present on yeast cells, but also on human erythrocytes group 0 and guinea pig red blood cells.

Please find attached links to articles that may help you to understand the binding of type 1 pili to their receptors.

Kind regards,

Beata

https://pubmed.ncbi.nlm.nih.gov/2895767/

https://www.jstor.org/stable/45861

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC264494/pdf/iai00134-0331.pdf

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