How much details we will be provided or is there any sample preparation steps present in this topic?

The talk will provide details on the design, characterization and applications of our avidity-based sensors to detect Ub–nucleosomes in mammalian cells. The main focus will be on our sensor to detect the DNA damage-associated H2AK13/15Ub. In the second part, I will present a protocol to assess the real-time recruitment of H2AK13/15Ub readers to DNA double-strand breaks. General details on sample preparation will be provided and more specific details can be provided upon request.