Is the pore size of the nuclear membrane pore complex after purification comparable to the intracellular pore seize?

The work of several groups (including ours) indicate that the size (diameter) of the purified NPCs is smaller than the one of an in-situ NPC in an actively growing cell. It is however quite similar to the size of an in situ NPC in cells where active transport and nuclear envelope tension have been reduced. Thus the NPCs could undergo a dilation-constriction cycle that seems to be related to the nuclear envelope tension.