Automatic determination of optimal cluster number

Thank you very much for your interest in our work! The Matlab script that was used to determine the optimal number of clusters can be found here: https://github.com/elifesciences-publications/immuneTopography/blob/master/step_03b_findOptimClust.m The core function in this script is the Matlab function "evalclusters" which is extensively documented here: https://de.mathworks.com/help/stats/evalclusters.html. These links should allow you to reproduce the procedure for your project. Hope that helps!