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Data was tested for normality using the Shapiro–Wilk test. Unpaired two tailed t test (for parametric data) or the Mann–Whitney U test (for non-parametric data) was used for comparison between two groups. One-way ANOVA, with Tukey post hoc analysis, or the Kruskal–Wallis test, with Dunn post hoc analysis, were used for comparisons between three or more groups, for parametric and non-parametric data, respectively. Survival data was analysed using the Mantel-Cox test. Results were considered as significantly different when p < 0.05.
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