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Study design and setting

TZ Tobia Zanotto
TM Thomas H. Mercer
ML Marietta L. van der Linden
PK Pelagia Koufaki
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A cross-sectional study design was used to explore the diagnostic accuracy of frailty-related screening tools (e.g. objective and subjective measures of physical function), utilising the Fried phenotype as reference standard, in a convenience sample of people receiving HD. The study was conducted in three Renal Units located in Fife and North Lanarkshire, United Kingdom, between October 2015 and August 2018 (trial registration ID: NCT02392299). All frailty-related and clinical measures were collected during a single assessment, which was performed by a trained researcher on a non-dialysis day (during the midweek interval). The study conformed to the ethical principles for medical research involving human participants, as outlined by the world medical association declaration of Helsinki, and received ethical approval by the Queen Margaret University and West of Scotland NHS Research Ethics Committees (NHS REC reference number: 15/WS/0079).

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