The study was approved in 2018 by the Ethical Review Board of Cliniques universitaires Saint-Luc/UCLouvain (V1 04/12/2018). All methods were carried out in accordance with relevant guidelines and regulations. All participants provided written informed consent.
Animal handling and experimental procedures were approved by local authorities at UCLouvain (Comité d’éthique facultaire pour l’expérimentation animale, 2016/UCL/MD/027) and performed in accordance with the Guide for the Care and Use of Laboratory Animals, published by the US National Institutes of Health (NIH Publication, revised 2011). All the authors complied with the ARRIVE guidelines.
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