Parameters, PSV, RI, peak diastolic velocity (VD), PSV/VD (VS/VD), and velocity-time integral (VTI) in the CCAs were continuously recorded for 10 s and then were calculated for mean value.
The mean IDs of all arteries were calculated as:
where IDsys and IDdia are the systolic and diastolic diameters, respectively.
RI was analyzed only in the carotid arteries because, as a measure of cerebral resistance, it is closely associated with cardiovascular risk was calculated as:
where PSV is the peak systolic velocity (PSV), and EDV is the end-diastolic velocity (EDV).
Flow rate (FR) was calculated from the vessel diameter, cardiac period, and velocity-time integral as:
where VTI is the averaged velocity-time integral, and T is the averaged cardiac cycle time.
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