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Statistical Analysis

NG Neha P. Godbole
RS Reza Sadjadi
MD Madeline A. DeBono
NG Natalie R. Grant
DK Daniel C. Kelly
PJ Peter F. James
CS Christopher D. Stephen
MB M. David Balkwill
RL Richard F. Lewis
FE Florian S. Eichler
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All statistical tests were performed in GraphPad Prism version 8.0.0 (San Diego, CA, USA) and significance was designated as two-tailed P < 0.05 with Bonferroni correction for multiple testing. Non-parametric testing with Bonferroni correction for multiple testing, including Mann-Whitney U-test, was used to compare the following groups: patients and healthy controls, male and female patients, patients who did not fall during SOT and patients who did fall during SOT.

Binormal receiver-operating characteristic (ROC) curves were generated for each of the gait assessments, (6MW, TUG, 25FW) by SOT falls. This was done to assess the capability of these measures to predict fall risk and determine cutoff values. Lastly, we used Spearman rank-order correlation to analyze the association between performance on clinical outcome measures and SOT scores as well as the number of falls during SOT.

Copyright and License information:  ©2021 Godbole, Sadjadi, DeBono, Grant, Kelly, James, Stephen, Balkwill, Lewis and Eichler.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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